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Biomedical subjects

J Laskawiec

Publications and source records attributed to J Laskawiec.

9 recordsLinked to original sources
PubMed1998

[Use of electron scanning microscopy and technical mechanics methods for determination of prolonged usefulness of Polfix plates after clinical use].

The paper deals with mechanical properties and structural changes within POLFIX external fixator plates used for tibial fracture treatment. The results indicate strengthening of the ALSI 316 L steel in the course of using of the plate. Structural comparison between the new and used implant showed insignificant increase of fatigue features within the plate. Overall results allow for multiple use of POLFIX plates.

Biocompatible Materials↗
PubMed1996

[The use of x-ray microanalysis and transmission microscopy in studies of the chemical composition and ultrastructure of the microregions of precancerous tissues of the larynx].

The authors have presented the results of studies concerning the changes of chemical composition and ultrastructure of tissue microregions at patients with laryngeal precancerous states. Microanalytical studies were made using X-ray JEOL JSM 35 microprobe analyser. The chemical composition of laryngeal precancerous tissue taken from the patients and a control group was estimated. The results of studies were verified using X-ray PHILIPS XL-30 microanalyser. Studies of tissue ultrastructure changes were conducted using JOEL JEM 100 XC transmission microscope. Some heavy metals like, lead, cadmium, nickel, iron, copper and caesium were found in the tissue from larynx precancerous state. Further more, in analysed biologic material there were noticed various degenerative changes within stratified squamous epithelium.

Adult↗
PubMed1995

[Use of x-ray microanalysis and scanning electron microscopy to determine reactivity to the Weller endoprosthesis by body parts].

The long-term immunity against penetration of alloy components from the Weller stem into the bone cement and bone tissue has been investigated. No alloy elements (Co, Cr, Mo) contamination within cement or bone tissue has been observed in patients included in this study. The method employed proved valuable for chemical analysis within microareas of the hip after arthroplasty.

Alloys↗
PubMed1992

[Qualitative determination of chemical compounds in the tissue of laryngeal cancer by x-ray microanalysis].

The authors presented the results of chemical compounds in the laryngeal cancer tissue in 20 patients with clinically and histologically confirmed plano-epithelial carcinoma using own modification of x-ray microanalysis method. Comparison between the healthy and neoplasmatic tissue showed as follows: 1) both healthy and neoplasmatic tissue showed the presence of Cd, Zn, Fe, Mn, Mg and Si, P, S, Cl, K, Ca, Ti; 2) the neoplasmatic tissue showed the presence of Pb whereas it was not observed in the healthy tissue; 3) both Pb and Cl were irregularly concentrated in the neoplasmatic tissue while in the healthy tissue showed regular concentration. The authors discuss some methodological aspects and try to interpret the obtained data in the view of toxic, mutagenous and carcinogenous role of the Pb.

Adult↗
PubMed1991

The trial of quantitative determination of the lead, chlorine, and sulfur content in the peripheral blood lymphocytes from patients with cancer of the larynx using the X-ray microanalysis method.

Using own modification of X-ray microanalysis method the authors evaluated the lead, chlorine, and sulfur content in the peripheral blood lymphocytes in 20 patients with laryngeal carcinoma in comparison with 20 healthy subjects of the control group. In patients with advanced clinical stages of that carcinoma the elevated lead and chlorine content has been stated in above cells whereas that of sulfur was decreased. According to the authors' opinion above changes reflect functional disturbances of lymphocytes in the patient with laryngeal carcinoma related to the decreased detoxicative properties, the intracellular electrolyte imbalance, and the enzymatic machinery alterations within that cells.

Adult↗
PubMed1989

[Superficial structure of lymphocytes from peripheral blood in patients with laryngeal cancer examined by scanning electron microscopy].

In 20 laryngeal cancer patients and in 20 normals 1927 and 1950 respectively the blood lymphocytes were examined by use of scan microscopy. The great differences were disclosed between the patients and normals. It was pointed out the considerable differences between patients and normals in the number of lymphocytes with plain surface (lymphocytes "G") in opposition to the intermediary and ciliated lymphocytes (differences statistically significant). In laryngeal cancer patients there were the significantly lower number of lymphocytes with ciliated surface (lymphocytes "Sz"). In the patient group there were the considerable differences in superficial structure of lymphocytes, probably as a response to cancer disease.

Adult↗
PubMed1988

The surface structure of peripheral blood lymphocytes from patients with laryngeal carcinoma evaluated by scanning electron microscopy.

Using the scanning electron microscopic technique the surface structure of the peripheral blood lymphocytes has been studied in 20 men aged 46 to 62 years with the laryngeal carcinoma diagnosed clinically and histopathologically. The control group consisted of 20 healthy men aged 39 to 58 years. According to the international classification 15 of 20 patients studied showed the T3N0M0 stage of the disease and other five the T4N0M0 stage respectively. The peripheral blood lymphocytes of the patients showed significantly greater variability of the surface structure as compared with the controls. The characteristic pattern of the lymphocytes in patients with cancer of the larynx was quantitative increase in numbers of lymphocytes having smooth surface deprived of microvilli and significant decrease of cells exhibiting numerous surface microvilli; these cells may correspond to the T and the B cell series, respectively. Moreover, the patients showed significant, approximately threefold increase in number of lymphocytes having the intermediate surface morphology between above mentioned two basic lymphocyte topographical types. According to the authors opinion above differences between the lymphocytes of patients with cancer of the larynx and those from healthy subjects are associated with the antitumor response of the lymphocytes.

Adult↗
PubMed1988

The X-ray microanalysis method for investigation of chemical composition of normal and pathologic human peripheral blood lymphocytes.

The X-ray microanalysis method for investigation of chemical composition, mainly trace elements, of normal and pathologic human peripheral blood lymphocytes has been presented. The method in question consists of two stages. During the first stage the scanning electron microscope with the energy dispersive X-ray spectrometer has been used. The second stage of the method consisted of employing the above microscope with the microwave dispersive spectrometer. The method enables the short-term determination of the various elements content within the lymphocytes with particular insight into the content of elements in a single cell. The preliminary investigations showed significant differences in the content of chlorine, sulfur and lead in normal human lymphocytes and that from patients with cancer of the larynx.

Carcinoma, Squamous Cell↗