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Biomedical subjects

J Lavieille

Publications and source records attributed to J Lavieille.

At least 19 recordsLinked to original sources

Stereotactic CT localization and biopsy of brain tumours using the Leksell frame. A study of 45 cases.

The authors have explored 45 patients presenting with clinical and CT evidence of space-occupying process in the brain. They endeavoured to determine the nature of the processes by performing stereotactic biopsy after localization by CT in 43 cases, by magnetic resonance imaging in 2 cases and by angiography in 1 case. The method proved reliable: the quality of the biopsy specimens obtained enabled the pathologist to make a satisfactory diagnosis by light microscopy after freezing in almost every case. Moreover, the orifice of penetration of the Leksell-Sedan needle provided a very accurate localization of the lesion when surgery was needed. Several specimens were taken during each session, since histological findings may vary according to the site of biopsy. All explorations were carried out under local anaesthesia. Two cases of haemorrhage were recorded; they were without long-term consequences but required surgery.

Biopsy↗

[Magnetic resonance imaging in rheumatology].

The authors report their experience with magnetic resonance imaging in rheumatology, established on more than 250 examinations. The method seems interesting for the study of discal and somatic spine diseases, and especially for the evaluation of tumor extension, the diagnosis of herniated disc, the diagnosis of spondylodiscitis, the exploration of the cervico-occipital joint. As compared to tomodensitometry, this method presents at the same time advantages and drawbacks. Peripherally, magnetic resonance imaging is useful for the exploration of bony tumors and evaluation of their extension. It gives excellent images of the knees and the hips where it seems to improve the results of tomodensitometry and bony scintigraphy in the diagnosis of osteonecrosis. It is likely that advances will broaden the scope of the indications and capabilities of this method.

Arthritis, Rheumatoid↗

[The brain scan and cervical artery lesions. Correlations: clinical-arteriographic-scanning].

Cerebral angiography and CT brain scan are performed on a group of 174 patients (28 asymptomatic patients; 109 patients with symptoms of stroke in relation with a clinically defined vascular territory; 37 patients with symptoms in relation with a clinically uncertain vascular territory). Angiographic findings are: cervical artery lesions in 143 patients, brain artery lesions in 6 patients, both extra and intra cranial artery lesions in 22 patients, and non atheromatous artery lesions in 3 patients. CT brain scan shows: hypodensity in 19 cases, hyperdensity in 1 case, cortical and/or sub cortical atrophy in 141 cases. Only 13 patients have normal CT brain scan. Authors also note: 4 infarction areas in asymptomatic patients and only 4 hypodensities out of 21 cases of internal carotid artery occlusion. Ulcerated cervical artery lesions seem to be the main cause (73%) of cerebral infarction.

Arterial Occlusive Diseases↗

[Tumors of the glomus jugulare].

Tumours of the glomus jugulare always raise diagnostic and therapeutic problems. We decided to review the pathology and clinical findings whilst reporting a typical case found on our neurology unit. After a brief review of the embryology, anatomy and histology of the glomus jugulare, the authors report the case of a patient who presented a recurrent intracranial form with involvement of several cranial nerves, together with associated involvement of the carotid glomus. This was a familial disease. The patient was operated on with excellent results. The authors then present a clinical description of the various signs in glomus tumours,; depending more on the origin of the tumours than on the length of history. They then criticize the diagnostic interest of radiology, emphasizing the interest of angiography which may demonstrate a pathological vascular focus derived from the internal carotid artery together with the vertebro-basilar system. Retrograde jugulography also provides important information. The treatment of glomus jugulare tumours is, above all, surgical. They are approached through the ear in order to localise the intra-petrous part, or else, they may be approached through the skull. A combined otological and neuro-surgical approach to sometimes necessary for the lesion may involve both the petromastoid region and the posterior cerebral fossa. Radiotherapy is often advised after operation, in view of the importance of the vascular component of these tumours. The results of treatment are, on the whole, satisfactory.

Female↗