Biomedical subjects
Publications and source records attributed to J Lawniczak.
Managed care has been offered as the savior of the Medicare program. But is it really the answer to Medicare's cost problems? What are the difficulties involved in this controversial issue, and what must be done before managed care can truly be considered a viable option for Medicare patients?
The lens fiber-cell plasma membrane MP26 from chick, bovine, and human lenses yielded identical cyanogen bromide peptide maps, confirming the essential conservation of structure in the junction protein of vertebrate lens fiber cells. Immunoblot analyses of the cyanogen bromide peptide maps of human lens MP26 and of its age-dependent proteolytic product MP22 confirmed that MP22 is a derivative of MP26. The findings in this study are the first consistent with the positioning of the methionine residues in lens MP26 as predicted by its cDNA-derived sequence.
Antibody prepared against chick lens vimentin cross-reacts with chick fibroblast vimentin and with vimentin of mammalian, reptilian, amphibian and fish lenses. This protein is localized in the epithelial and cortical fiber cells and is progressively lost from the deeper cortical cells. It is absent from the nuclear cells. Lens vimentin is readily oxidized to form high molecular components.