In recent years disturbances in releasing neurotrophic growth factors have been viewed as one of the causes of the development of Alzheimer's disease. It is assumed that abnormalities concerning neurotrophic growth factors (e.g. disturbances in releasing them and (or a wrong response of nerve cells to released growth factors) may be co-responsible for the development of abnormal functions of recent memory or concentration. It is assumed that their role in neurodegenerative processes consists primarily of increasing the survival rate of nerve cells and exerting an effect on the transmitting functions of CNS neurons. Attempts made at present to use growth factors in A.D. with a view to increasing the survival rate of degenerating nerve cells and improving the transmitting functions of neurons will be continued in future in pace with the advancement of our knowledge of their mechanisms.

Acetylcholine↗

PubMedDate not supplied

[Successful therapy of the psychiatric patient with catatonic paranoidal syndrome and monitoring of induced cytokine production].

The paper reports the case of a 42-year-old woman with a diagnosed catatonic-paranoidal syndrome and a noted dysfunction as regards lymphocyte subpopulation and the production of some cytokins: Tumor Necrosis Factor (TNF) and interferons (IFN). As the first phase of the treatment had proved unsuccessful and there appeared symptoms hinting at the possibility of a subclinical inflammatory process in the brain, parallel to psychiatric therapy, treatment was instituted in the system of successive three-week cycles with Tołpa's Peat Extract (PTT), Selenium and Zinc on a natural yeast basis (Selenium and Zinc preparations) as well as with encortone. After a month of treatment a complete clinical remission was achieved as well as normalization as regards all the tested immunological markers.

Adult↗

PubMedDate not supplied

[Clinical interpretation of a case of severe catatonia].

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Acute Disease↗