Biomedical subjects
Publications and source records attributed to J Lewin-Epstein.
Two cases of scrofula are presented. These cases were very different in terms of age of the patient, duration of the lesion, and the clinical course. The final diagnosis was based on the histologic findings and tuberculin tests.
Chondromyxoid fibroma is a benign skeletal tumor which rarely affects the jaws. Only 10 cases have been found in the literature, all of them located in the mandible. In the present articles, 2 additional cases are described, one of them being the first reported case located in the maxilla. Up-to-date clinical and pathological data of 2 reported cases and a review of the literature are presented.
Marsupialization is a surgical technique that may be preferred to enucleation in treatment of benign cysts. The acrylic resin obturator maintains the surgical opening during healing and assures success of the surgery. Two basic techniques to construct a stable and retentive obturator prosthesis were described.
The use of polydimethylsiloxane prostheses to improve facial appearance in patients with Down's syndrome is reported. In 1 year, 50 patients were treated with 120 prostheses. A follow-up of 8 to 18 months showed that a low incidence of minor complications occurred. Combined with the satisfactory results experienced, this makes the procedure safe and desirable.
Explore the source record for details and available documents.
The late effects of surgical exposure of unerupted teeth were analyzed. Of 121 teeth, 62 had only the crowns exposed; additional traction was applied to 31 teeth and 28 were repositioned. Postoperative observation time ranged from eight months to 13 years. One hundred and eleven teeth assumed their position in the arch and were deemed successfully treated; ten teeth failed to erupt. Of the successfully treated teeth, 23% showed biological aberrations such as obliteration of the pulp, dwarfed roots, and denervation. These pathophysiologic changes, alone or in combination, were commensurate with the amount of trauma inflicted on the teeth. Teeth that wer repositioned showed the most change, whereas teeth that only had crowns exposed showed the least change.
Complete agenesis of both parietal bones was found as a single anomaly in an otherwise healthy boy. The defect in the cranial vault was restored with performed methyl methacrylate onlay plates.
A 19-year-old woman presented with two tumorlike conditions in the mandible. Seven vital mandibular teeth were associated with periapical lesions. One periapical lesion was enucleated and histopathologic examination confirmed the diagnosis of periapical fibrous dysplasia. The second lesion was a large multilocular radiolucency which extended from the mandibular left premolars to the ascending ramus. It was diagnosed as a central giant cell granuloma despite having many features in common with those of an ossifying fibroma. The lesion was removed and healing was uneventful.
Mural ameloblastomas are estimated to constitute 5% of all ameloblastomas. Although resembling the total ameloblastoma population in terms of predilections for sex and site, the average age of the patients with mural ameloblastoma, in comparison with the total group, was 21.8 vs 38.9 years. Eighty-five percent of the mural ameloblastomas were associated with follicular cysts, all of which were observed before the age of 30. The frequency of recurrence after simple enucleation of the cyst containing this lesion is considerably lower than that for ameloblastomas in general that are treated in a similar manner. Therefore, further and more extensive surgery for mural ameloblastoma is justified only in the event of recurrence.
The most common etiologic factor responsible for the intermittently suppurating cutaneous sinus tract about the face and neck is the extension of chronic infection of dental origin. Complete healing invariably follows the eradication of this source of infection. The presence of a cutaneous sinus tract about the face and neck should alert members of the profession to the necessity of routine dental examination including roentgenographic surveys of the teeth and jaws.
The morphologic structure of anorganic dental calculus was studied by means of the scanning electron microscope. From surface observations, calculus is apparently composed of two components with distinguishable patters of calcification. One component is formed by the precipitation of minute calcific crystals on microorganisms and intermicrobial substances (plaque matrix). Such calcified masses, often spherical in shape, have a sponge-like appearance with empty spaces representing the former sites of entombed and degenerated organisms. Thus, intracellular calcification is not evident at this stage of calculus development. The other component, although having at least one common calcification front with the former, does not appear to be directly associated with microbial calcification. It exhibits a configuration of generally larger crystal growths of varying shapes and sizes. These two calcification patterns are comparable, both in distribution and size, to what has been observed by means of the transmission electron microscope, and what Schroeder has designated as "types A & B centers of mineralization," respectively. The calcific precipitation in type A centers have been identified by X-ray diffraction as hydroxyapatite. It is, therefore, speculated that the crystal patters in type B centers might represent other known forms of calcium phosphates present in calculus, such as octacalcium phosphate, whitlockite and brushite.
The effect of long standing mechanical irritation of the tongue was studied in 100 young rats. This was effected by the protruding end of a twisted wire, ligated around the lower first molar and directed toward the later-ventral aspect of the tongue on one side, while the other side served as control. Groups of rats were killed after 3, 6, 9 and 12 months and the tongues were examined grossly and microscopically. Fibrous hyperplasia was observed in 48% of tongues in the 3-month group and increased to 79% in the 12-month group. Microscopically, epithelial changes were noted which included ulceration acanthosis and hyperkeratosis. In no instance was dyskeratosis or any other malignant change noted.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.