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Biomedical subjects

J Link

Publications and source records attributed to J Link.

33 records · Page 2Linked to original sources

Changes in intracranial pressure associated with extradural anaesthesia.

The intracranial pressure (ICP) response to the lumbar extradural injection of bupivacaine hydrochloride was measured in two patients on a total of 29 occasions. In the first patient, mean ICP increased from an average figure of 18.8 mm Hg to 39.5 mm Hg after the injection of 10 ml of solution. This increase was maintained for an average of 4.5 min. Both the magnitude and the duration of the increase were less when 5 ml was injected. The second patient had a normal baseline ICP, but the injection of bupivacaine 10 ml produced an increase from a mean of 9.3 mm Hg to 15.6 mm Hg. Injection of the same volumes of physiological saline in the second patient induced increases in ICP similar to those obtained with bupivacaine. There was a good correlation between baseline ICP and the increase produced by the extradural injection. It is concluded that extradural anaesthesia must be used with extreme caution in patients with reduced intracranial compliance, and should not be used at all in a patient with intracranial hypertension or a space-occupying lesion.

Adult

Melanoma in a patient treated for psoriasis.

Psoriasis, ultraviolet light, and coal tar have been associated with the development of cutaneous malignancy. We have described a 32-year-old psoriatic man who developed a melanoma after 16 years of treatment with ultraviolet light and coal tar. This is the only case of melanoma occurring in a patient treated for psoriasis reported in the world literature.

Adult

[Nitrous oxide in the working environment of anaesthetic personnel. A gas chromatographic analysis (author's transl)].

Nitrous oxide as well as halothane is hazardous for organ dysfunction in chronically exposed man. It is necessary for each anaesthetist, in cooperation with the hospital authorities, to take care to eliminate overflow not only of halothane but also of nitrous oxide from anaesthetia locations. Using gas chromatography, we studied the concentration of nitrous oxide during routine daily work in the environment of anaesthetic personnel. With our method of discharging anaesthetic gases, we were able to reduce the concentration of nitrous oxide.

Air Pollutants

[Control of respirator pressure and drainage of the anesthetic gases with Kuhn's device in pediatric anesthesia (author's transl)].

By adding a manometer and a pressure valve to the anaesthetic equipment used for newborns and children (Ayre-T-piece, modified by Kuhn) we are able to control airway pressures continuously and to draw out all narcotic gases from the operating room. The concentration of halothanee thus can be diminished to a very low level around the aneasthesist and the surgeon.

Air Pollution

[The concentrations of halothane in the operating theatre and its dependance on various methods of removal (author's transl)].

Measurement of halothane concentrations by means of gas chromatography was used to compare the efficiency of 1) a filtration system and 2) ducting of gases into the exhaust of the ventilation system of our operating threatre. The concentrations were found to be lower when the latter method was used. Measurements made subsequently provided data on halothane concentrations occurring during routine service when different methods of anaesthesia were used, with and without ducting of gases into the ventilation exhaust system.

Air

[Intranarcotic infusion therapy -- a computer interpretation using the program package SPSS (Statistical Package for the Social Sciences)].

In a retrospective 18-month study the infusion therapy applied in a great anesthesia institute is examined. The data of the course of anesthesia recorded on magnetic tape by routine are analysed for this purpose bya computer with the statistical program SPSS. It could be proved that the behaviour of the several anesthetists is very different. Various correlations are discussed.

Adolescent

Self-monitoring of blood glucose: how accurate are children with diabetes at reading chemstrip bG?

Accuracy of self-monitoring of blood glucose (SMBG) using Chemstrip bG (Bio-Dynamics, Indianapolis, Indiana) was studied in 90 randomly selected children with insulin-dependent diabetes mellitus (IDDM). For 28 children (mean age 8.3 +/- 3.6 yr) a parent routinely read the Chemstrip at home. The remaining 62 children (mean age 13.7 +/- 2.8 yr) read the Chemstrip themselves. Each child or parent analyzed 20 capillary blood samples using Chemstrips and answered a questionnaire on SMBG. The accuracy of SMBG of the group was high (mean correlation coefficient = 0.89 +/- 0.05), but consistency of measurement was variable (mean standard deviation = 1.90 +/- 0.57) and there was a general tendency to underread Chemstrips (mean y-intercept = 1.05 +/- 1.48; mean slope = 0.80 +/- 0.17). For each subject, 0-65% (mean of 34%) of readings were within 10% of the laboratory measurement, and 17-100% (mean 68%) within 20%. These results indicate that most subjects were fairly accurate in reading Chemstrips; however, analysis of accuracy is useful in identifying individuals who are inaccurate or inconsistent in SMBG. Continuing supervision of SMBG is necessary in children with IDDM.

Adolescent