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J Loly

Publications and source records attributed to J Loly.

10 recordsLinked to original sources
PubMed1984

Renal control of cephalic and intestinal removal of glucagon in the anesthetized dog.

The extraction of plasma glucagon during intravenous infusion of exogenous hormone has been measured in the head, gastrointestinal tract or kidney of dogs submitted to binephrectomy or to sham surgery. A significant glucagon extraction was demonstrated not only in the kidney, but also in the head and in the portal area; moreover, plasma glucagon extraction by the head and by the bowel were significantly reduced, after binephrectomy, by 55 and 46 per cent, respectively. Changes in blood flow are unlikely to be involved to explain these phenomena. Therefore, a control by the kidney of the peripheral removal of plasma glucagon is suggested, the mechanism of which remains hypothetical.

Animals↗
PubMed1982

Renal control of the peripheral uptake of exogenous gastrin in the dog.

The extraction of plasma gastrin during intravenous infusion of exogenous hormone has been measured in the head, gastrointestinal tract, or kidney of dogs submitted to sham surgery, evisceration, or binephrectomy without or with subsequent kidney transplantation. A significant gastrin extraction was demonstrated not only in the kidney, but also in the head and in the gastrointestinal tract; moreover, plasma gastrin extraction in the head and the bowel was considerably reduced by binephrectomy and was brought back to control values after subsequent kidney transplantation. A non-specific effect of surgery and a variation in peripheral blood flow seem to be excluded. Thus a control by the kidney of the peripheral removal of blood gastrin is evidenced, the mechanism of which remains hypothetical.

Animals↗