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J Lommerse

Publications and source records attributed to J Lommerse.

4 recordsLinked to original sources

Prophylaxis of pleuropneumonia in pigs by in-feed medication with oxytetracycline and the subsequent transmission of infection.

The prophylactic effect of in-feed medication with oxytetracycline was tested by using an Actinobacillus pleuropneumoniae aerosol challenge model. Groups of 10 conventional pigs were provided with feed containing 400, 800, 1200 or 1600 mg oxytetracycline/kg and fed ad libitum. After six days of medication the pigs were challenged and clinical signs were recorded. Two groups of four unmedicated pigs served as controls and were euthanased 36 to 48 hours after challenge and dissected. The feed medication was continued for nine days after the challenge, and the different treatment groups were then moved to separate accommodation where they were mixed with seronegative tracer pigs. The steady state concentrations of oxytetracycline in the pigs' serum after six days medication with feed containing 400, 800, 1200 or 1600 mg oxytetracycline/kg ranged from 0.07 to 0.13, 0.21 to 0.46, 0.27 to 0.46 and 0.35 to 0.56 microgram/ml, respectively. One of the eight unmedicated control pigs died, and the other seven showed signs of pleuropneumonia post mortem. Medication with feed containing 400 mg and 800 mg oxytetracycline/kg failed to prevent pleuropneumonia in the challenged pigs, and the mortality rates in these groups were two out of 10 and one out of nine pigs, respectively. All the pigs given feed containing 1200 and 1600 mg oxytetracycline/kg survived and only two of the pigs in the first treatment group showed mild clinical signs. No clinical signs were observed in the tracer pigs which were mixed with the pigs medicated with 400, 800 or 1200 mg oxytetracycline/kg.(ABSTRACT TRUNCATED AT 250 WORDS)

Actinobacillus Infections↗

[Serological study of the presence of Actinobacillus pleuropneumoniae antibodies serotype 2 and 9 on pig-breeding farms in the provinces of North Brabant and Overijssel (The Netherlands)].

Serological studies for the presence of CFT antibodies to Actinobacillus pleuropneumoniae, both to serotype 2 and serotype 9, were done in twenty-five sows on each of thirty pig-breeding farms in the provinces of North Brabant and Overijssel. Antibodies to serotype 2 and/or serotype 9 were detected in one or several sows on forty-two out of sixty farms. Similar findings were recorded on eighteen and twenty-four farms respectively in the provinces of Overijssel and North Brabant; the number of herds showing positive reactions to serotype 2 was sixteen and twenty-three in these provinces respectively, that showing positive reactions to serotype 9 being six and five respectively. An average proportion of nineteen per cent of the samples taken on the farms having serologically positive animals was positive for serotype 2, and twelve per cent for serotype 9. Only one of the twenty-five animals on twelve farms was found to be positive; serotype 2 was present in ten cases and serotype 9 in two cases. A marked effect of the size of the herds on the serological status of the farms was not observed in the present studies. This was also true of the purchasing policy; there was no difference between farms which had no longer purchased any breeding pigs for an average period of seventeen years and for one year respectively. Clinical symptoms of an infection due to Actinobacillus pleuropneumoniae were only reported as occurring on two farms having serologically positive animals.

Actinobacillosis↗

[Serologic studies on the presence of antibodies against Haemophilus (Actinobacillus) pleuropneumoniae at swine breeding farms in North Brabant].

Serological screening for the presence of antibodies to both H. pleuropneumoniae serotype 2 and serotype 9 using the complement fixation test was carried out on twenty-nine piglets production farms of an integrated group in the province of North Brabant. Antibodies to H. pleuropneumoniae serotype 2 and serotype 9 were not detected on six of the twenty-nine farms when a single screening was performed. The proportions of farms with animals serologically positive in regard to serotypes 2 and 9 were 59 and 34 per cent respectively. Of the specimens on farms with seropositive animals, those positive for serotype 2 averaged 13 per cent, those positive for antibodies to serotype 9 averaging 9 per cent. When a re-examination was made within two months after the first screening, animals showing antibodies to serotype 2 or serotype 9 were present on three of the six pig-breeding farms which were negative for these antibodies at first examination. When a third investigation was carried out within two months after the re-examination, antibodies to serotypes 2 or 9 were also detected on the remaining farms which were negative for antibodies in the two previous investigations.

Animals↗