[Pustular lymphomatoid papulosis].
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Biomedical subjects
Publications and source records attributed to J Luelmo Aguilar.
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Melanocytic nevi are due to benign melanocyte proliferation. Most melanocytic nevi develop during childhood and adolescence and give an stabilization in middle age (already 25 years old). About 1% of newborns presents congenital nevi. Removal of nevi is not usually required except in cases of giant congenital nevi and clinically atypical nevi. The aim of this study was to review the different types of nevi, their possible associations and prevention of risk factors. Sun exposure, atypical or numerous nevi, phenotypical risk of nevi and familial antecedents of melanoma are predisposing factors for melanoma. Epidemiological studies confirm an increasing epidemic of melanoma in adults and evidence exists that this worldwide epidemic is also affecting the teenage population. Pediatricians play an important role in the prevention and early diagnosis of these lesions. They can also educate parents and children on adequate sun screening, which includes the use of sunscreens against ultraviolet A and B radiation, the wearing of protective clothing and the avoidance of overexposure to sunlight.
BACKGROUND: Eosinophilic pustular folliculitis (EPF) is an inflammatory disorder of unknown etiology. In infants this disorder is characterized by recurrent episodes of sterile pustules primarily or exclusively involving the scalp with occasional involvement of the face, trunk and extremities. There are few reports of EPF in children. OBJECTIVE: To describe the clinical features and evolution of four pediatric patients and to discuss the main differential diagnoses. METHODS: Biopsy specimens were examined, pustules were cultured and laboratory tests were analyzed. RESULTS: Four patients (3 males and 1 female) aged 7-18 months presented with self limiting recurrent pruritic papules and pustules on the scalp. In one patient, the lesions were mainly localized on the extremities. Cultures for bacteria, fungi and viruses were negative. No systemic disease was found. Topical steroids were effective in three patients but pustules recurred after treatment was stopped. Cetirizine and Hydroxacen were administered in two corticoid-resistant patients with fair response. No other systemic therapy was administered. Peripheral eosinophilia was detected in three patients. CONCLUSIONS: EPF in infants seems to be a clearly defined entity. Although few cases have been described in children, this dermatosis is undoubtedly more frequent than suggested by the literature. Consequently, pediatricians should be aware of its existence.
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