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Biomedical subjects

J Lustmann

Publications and source records attributed to J Lustmann.

At least 19 recordsLinked to original sources

Cleidocranial dysplasia: Part 2--Treatment protocol for the orthodontic and surgical modality.

The principles on which the present approach to the treatment of cleidocranial dysplasia are based were stated in part 1 of this article. Comparison was made with two other methods and the advantages of the present method were described in terms of (a) how this method is adapted to the clinical features of the condition, (b) when surgical intervention is appropriate, (c) how the dynamic appliance system may be adapted to the changing environment as more teeth erupt, and (d) the importance of rapidly bringing about the eruption of the anterior teeth. The practical aspects of the treatment are now described step-by-step with illustrations taken from the treatment of several different patients.

Adolescent

Cleidocranial dysplasia: Part 1--General principles of the orthodontic and surgical treatment modality.

Over several decades, occasional reports of dental treatment provided by an individual practitioner to patients suffering with cleidocranial dysplasia have appeared in the literature. In the past, the main treatment was prosthetic replacement. Orthodontic treatment has only recently been considered as a serious treatment option, with success being described in several aspects of this treatment modality, in published individual case reports. Given the rarity of the condition, guidelines for the treatment of cleidocranial dysplasia are difficult to find in the literature, because few practitioners have treated enough cases to be in a position to make such recommendations. Two different approaches have been proposed in the past and are discussed here. The relative advantages of a third approach are expounded in detail.

Child

Retrospective epidemiological study of Burkitt's lymphoma in Israel and diagnosis by a conservative incisional biopsy.

The clinical features of 74 patients with Burkitt's lymphoma diagnosed at the Hadassah Medical Center in Jerusalem, Israel, are described. The prompt diagnosis of a child with high grade malignant jaw involvement of non-Hodgkin's Burkitt's lymphoma is reported. The use of the open biopsy with special emphasis on the incisional biopsy is discussed in light of the incidental exfoliation of the two primary molar teeth and one permanent successor in this case.

Adolescent

Salivary gland involvement in Wegener's granulomatosis. A case report and review of the literature.

Late involvement of the parotid gland in a patient with a limited form of Wegener's granulomatosis is presented. We report the full course of the disease and the difficulties encountered in determining the nature of the parotid enlargement. We discuss the contribution of computerized tomography and ultrasonography to elucidate parenchymal morphologic findings and radioisotope studies to determine the functional capacity of the gland. In cases of Wegener's granulomatosis with salivary symptoms, measurement of salivary gland functional capacity, in addition to the c-ANCA test, may help to monitor disease activity. Despite the rarity of the disease, in cases when granulomatous diseases are considered, it should be recognized that Wegener's granulomatosis may result in salivary gland involvement.

Adult

Mandibular fractures in infants: review of the literature and report of seven cases.

Mandibular fractures in infants are rare. During the last 50 years, only 13 cases have been recorded in the literature. In this study seven cases of mandibular fractures in infants treated within a period of 3 years are reported. The male-to-female ratio was 6:1. All fractures were caused by short falls, and in all cases the symphysis region was the injured site. The treatment approach was conservative, without any active intervention. The results were satisfactory; perfect alignment of the fractured bone segments was achieved in all cases.

Accidental Falls

Ameloblastic fibrodentinoma: report on two new cases.

Brain heterotopia of the tongue is a rare, congenital malformation, probably not embryologically related to encephaloceles or to the so called "nasal gliomas." The progressive growth frequently noted confers to the lesion a tumor-like appearance and can raise a clinical suspicion of some rare neonatal neoplasia. The non-neoplastic nature of the lesion is well established, and the growth may well be due to the fact that heterotopic brain grows as rapidly as normal brain in the infant. Although local recurrence after incomplete resection has been reported, the clinical behavior of brain heterotopia of the tongue is benign.

Child

Gerodermia osteodysplastica: report on two patients and surgical correction of facial deformity.

We present four individuals with Gerodermia Osteodysplastica in a Jewish family from Morocco confirming the autosomal recessive inheritance of the disorder. Three previously unreported findings are described: a) enlarged funnel-shaped mandibular lingula; b) extension of the mandibular premolar and molar roots below the inferior dental canal, and of the second molars into the lower border of mandibular cortical bone; and c) hypercementosis of the maxillary incisors and mandibular molars surrounded by a radiolucent halo in several teeth. The facial deformity resulting from maxillary hypoplasia and mandibular prognathism was corrected by orthognathic surgery: Le Fort I maxillary osteotomy and vertical mandibular osteotomy.

Adult

Salivary and lacrimal gland involvement in a patient who had undergone a thyroidectomy and was treated with radioiodine for thyroid cancer.

A patient with bilateral, insidiously developing enlargement of the parotid glands that started 1 year after a total thyroidectomy and ablative radioiodine therapy (200 mCi I131) for papillary carcinoma is presented. The patient displayed prolonged periods of hypothyroidism accompanied by hypercholesterolinemia, notwithstanding hormone replacement therapy. Three years after surgery, parotid and lacrimal gland functions were reduced and fatty degeneration of the parotid parenchyma was demonstrated histologically. The submandibular and sublingual glands were preserved. It is suggested that the hormonal and metabolic derangements are responsible for the glandular dysfunction, rather than a direct effect of iodine on the glands.

Adult

Lichen planus: exploring its malignant potential.

Almost any area of the mouth may be affected by LP, but the most frequent locations are the cheeks, tongue and gingiva. The eight cases in our study illustrate the proliferative epithelial changes to verrucous or squamous cell carcinoma that can appear in oral LP. We also found a predisposition of LP in women. We urge, therefore, that clinicians monitor LP patients closely at three- to six-month intervals and attempt treatment for early resolution.

Adolescent

Photoacoustic injury and bone healing following 193nm excimer laser ablation.

The argon-fluoride excimer laser was investigated as a cutting-ablating tool for bone surgery. A total of 52 rats were divided into two experimental groups and two control groups. In one experimental group cortical bone defects were made; in another experimental group defects penetrating into the medullary space were performed. In the two control groups similar defects were achieved using water-cooled carbide burs. The rats were sacrificed on each of the 3, 7, 10, 20, 30, and 40 postoperative day. The cortical bone, the medullary space, and the extrabony tissue were examined by means of light microscopy. In both experimental groups, bone damage, represented by osteocyte destruction, extended to 1,050-1,450 microns ahead from the irradiated site, and bone healing was very much impaired. In the control groups no histological changes could be identified and bone healing appeared to be within normal limits. We believe this extensive bone damage, following 193 nm irradiation, to be a result of photoacoustic waves propagating in the bone following each pulse. In view of our results we feel that excimer lasers presently in use are not suitable for bone surgery. This problem of photoacoustic damage can be overcome in one of two ways: by designing a CW excimer laser or by reducing the pulse width to the picosecond regime.

Animals

Lip carcinoma in renal allograft recipient with long-term immunosuppressive therapy.

Five years after a kidney transplant and immunosuppressive therapy a 42-year-old woman had squamous cell carcinoma of the lower lip with an innocent appearance. We present this as the first case of lip squamous cell carcinoma in a kidney transplant recipient to be reported in the dental literature. We review the medical literature.

Adult

193 nm excimer laser ablation of bone.

The argon fluoride excimer laser is investigated as a cutting-ablating tool for bone surgery. Quantitative measurements are presented for various fluences of laser energy and number of pulses. Histological data are presented that demonstrate the minimal damage to the surrounding material from the laser interaction. Comparisons are made for non-decalcified and decalcified bone. The differences observed, as a function of decalcification in the fluences required for specified depth penetration, are noted and a possible explanation is suggested.

Animals

Relation of pre- and intraoperative factors to prognosis of posterior apical surgery.

The relation of preoperative and intraoperative factors to the prognosis of apical surgery was studied in 136 premolar and molar roots. The evaluated factors were: clinical signs and symptoms, size of the periapical lesion, root canal obturation, tooth restoration, apical retrofilling, and the operating surgeon. A significantly higher success rate was found in roots obturated 2 mm or shorter of the apex, in roots without post restoration, and after retrofilling of roots with apparently well-condensed obturation. The prognosis differed significantly following treatment by various operators but was unrelated to their experience.

Apicoectomy

Treatment results of apical surgery in premolar and molar teeth.

The purpose of this investigation was to study long-term treatment results following apical surgery in premolars and molars. These results were assessed by reexamination of 136 roots on which apical surgery was performed. The observation period varied from 6 months to 8 yr. According to radiographic and clinical criteria, the treatment results were considered successful in 44.1% of the roots, doubtful in 22.8%, and unsuccessful in 33.1%. Clinical signs and symptoms were associated with 33.1% of the roots, occurring significantly more in roots demonstrating radiographically unsatisfactory healing. The results are discussed with reference to other studies on apical surgery in posterior and anterior teeth. However, methodological differences do not permit the drawing of direct comparisons to those studies.

Adolescent

Gaucher's disease affecting the mandible and maxilla. Report of a case.

Gaucher's disease is a rare autosomal, recessive disorder characterized by deficiency of lyzosomal hydrolase glucocerebrosidase, and showing predilection for Ashkenazi Jews. A case of Gaucher's disease affecting both jaws and initially diagnosed by mandibular biopsy is described.

Diagnosis, Differential

Squamous odontogenic tumor. Review of the literature and case report.

Squamous odontogenic tumor (SOT) is a rare, benign odontogenic tumor affecting both jaws in all age groups. The tumor is composed of squamous epithelial islands surrounded by a mature connective tissue stroma. This tumor may occasionally be misdiagnosed as ameloblastoma, squamous cell carcinoma, verrucous carcinoma and keratoacanthoma. A conservative surgical approach is the recommended treatment. An additional case is reported and the literature reviewed.

Child

Sialolithiasis. A survey on 245 patients and a review of the literature.

245 patients with sialolithiasis, treated during a period of 20 years, were evaluated and the literature has been reviewed. The submandibular gland was involved in 231 patients, the parotid gland in 11 patients, and the sublingual gland only in 1 patient. There is some indication that patients with sialolithiasis are more prone to develop nephrolithiasis. A relationship with other systemic disorders could not be detected. Laser treatment seems to be a promising treatment modality for stone removal, even in acute phases.

Adolescent