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J Lutter

Publications and source records attributed to J Lutter.

11 recordsLinked to original sources

[Duplex ultrasonography of the portal circulation before and after sclerotherapy of esophageal varices].

Authors examined 40 patients suffered from portal hypertension before and after sclerotherapy of esophageal varices with duplex ultrasonography. The patients were divided into four groups: the first and recurrently bleeding patients and those who were treated with propranolol. The average velocity of the main portal vein before the treatment was significantly lower in the patient group, than in the normal control group. There were no significant changes observed after treatment. The portal blood flow increased in the first bleeding patients who did not take propranolol. The diameter of the main portal vein increased in the recurrently bleeding patients. The conclusion is, that the duplex ultrasonography of the portal circulation is a valuable noninvasive method. One has to take into consideration the limits of this technique and further data are needed for the diagnostic and prognostic accuracy.

Esophageal and Gastric Varices↗

[Comparative observations of internal and external quality controls in the districts of Neubrandenburg and Rostock].

A useful combination of results from internal quality control and external quality assessment is possible only if the statistical procedures of both systems involve the same limits to accept control data. These limits are shown. For 45 laboratories expected quality groups QG-T are calculated from results of internal quality control. Quality groups QG-RVL are calculated from results of external quality control assessment. In 30 cases the great difference of QG-T and QG-RVL is supposed to be caused by inaccurate performance of internal quality control.

Germany, East↗

The potency testing of diphtheria and tetanus toxoids as determined by the induction of antibody in mice.

An antibody induction (AI) assay in mice has been developed for the potency testing of diphtheria and tetanus toxoids. A diphtheria-pertussis-tetanus served as a reference preparation so that both toxoids could be tested within the same experiment. Results have been compared with those obtained by the conventional lethal challenge tests in guinea pigs (diphtheria) and mice (tetanus). The potency values obtained in the AI tests reflected the differences in the toxoid content of the preparations. Being an economical method, the AI test can be recommended for the potency control of DPT vaccines subject to confirmation of the authors' observations by others.

Animals↗