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Biomedical subjects

J M Abad

Publications and source records attributed to J M Abad.

16 recordsLinked to original sources

Choledochoduodenostomy and sphincterotomy in the treatment of choledocholithiasis.

Over a 10-year period, 2610 patients underwent operation for biliary lithiasis. Exploratory choledochotomy was indicated in 591 patients (22.6 per cent). This was followed by simple choledochorrhaphy over a T tube in 240 patients (40.6 per cent), transduodenal sphincterotomy and choledochorrhaphy over a T tube in 126 (21.3 per cent), supraduodenal choledochoduodenostomy in 216 (36.5 per cent), and choledochoduodenostomy and transduodenal sphincterotomy in nine (1.5 per cent). Choledochoduodenostomy was performed if the bile duct was more than 12 mm in diameter. The indication for transduodenal sphincterotomy was the presence of a stone impacted in the papilla and/or papillary stenosis. Six patients developed abdominal abscess and three an external biliary fistula following choledochoduodenostomy. There were four abscesses and two episodes of acute pancreatitis in patients undergoing sphincterotomy. There was no difference in mortality rate between the two groups. After a mean follow-up of 5.6 years, 71.5 per cent of patients who underwent choledochoduodenostomy and 75.2 per cent of those who received transduodenal sphincterotomy were asymptomatic. The remainder suffered from dyspepsia, colicky pain or episodes of cholangitis. Nine patients underwent reoperation for residual calculi (six choledochoduodenostomies, three sphincterotomies).

Adult

Brain cysticercosis treated with praziquantel. Report of six cases.

Cysticercosis is the most common parasitosis affecting the central nervous system and it is endemic in many countries. Although cysticercosis is nowadays a rare disease in Spain, three of such cases have been treated with Praziquantel at the Hospital "Princesa Sofía" of León and another three at the Hospital General de Galicia of Santiago, and the six of them are reported together. The six patients presented at CT scans cysts located at different levels in the brain parenchyma, subarachnoid space and ventricular system. Praziquantel was administrated at daily dosage of 50 mg per kilogram of body weight, by oral route, distributed in three doses during 15 days. Moderate hepatotoxic effect were detected in two cases. No significant neurological disfunction was observed in any case during the treatment. The therapeutic effect on the brain cysts was evaluated in the CT scans obtained after treatment. In four cases a positive effect on the cysts was observed, but no apparent effect was noticed in the other two.

Adult

An unrecognized neurological syndrome: sixth-nerve palsy and Horner's syndrome due to traumatic intracavernous carotid aneurysm.

An unclassified type of ophthalmoplegia, composed of sixth-nerve paresis and Horner's syndrome without facial anhidrosis, was studied in an 18-year-old woman following cranial trauma. Carotid angiography disclosed a traumatic intracavernous carotid aneurysm. According to previous anatomical reports, an important sympathetic nerve joins the sixth cranial nerve in the posterior part of the cavernous sinus. An expansive process into the cavernous sinus at this point may cause this unclassified neurological syndrome. A review of the literature and a detailed clinical study were made.

Abducens Nerve

Cerebral arteriovenous malformations. Comparative results of surgical vs conservative treatment in 112 cases.

A group of 112 patients affected by cerebral arteriovenous malformations is reviewed. Sixty-six per cent of the cases presented with subarachnoid hemorrhage. Epilepsy was the main clinical feature in 20% of the cases. In 45 cases an intracerebral or intraventricular hematoma was diagnosed by CT-scan, angiography or was found during surgery. Seventy cases (62.5%) were operated upon and 42 cases were treated conservatively. In 57 operated cases, total excision of the AVM was confirmed by postoperative angiography. In this group there was no rebleeding during the follow-up period. Other 13 cases were submitted to partial excision of the AVM or clipping of the feeding vessels. In this latter group, 2 patients had later subarachnoidal rebleeding. Operative mortality was 11% in this series. Mortality caused by the AVM in the non-operated group was 20%. Comparing the morbidity in both groups, the operated group had a much better clinical evolution than the non-operated one. Regarding the final clinically results, an abnormal state of consciousness before surgery, a large size of the AVM and the presence of intracerebral hematoma appear to have a bad prognosis significance.

Adolescent