[Anesthesia in Wilson's disease].
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Adult↗
Biomedical subjects
J M Abengochea Beisty
Publications and source records attributed to J M Abengochea Beisty.
[Metabolic and immune response to spinal vs intravenous morphine for analgesia after radical prostatectomy].
OBJECTIVE: To study differences between the endocrine-metabolic and immune cell responses to spinal or intravenous administration of morphine for analgesia after radical prostatectomy. MATERIAL AND METHODS: Prospective study of 60 patients randomized to 2 groups: in group A (n=30) morphine for postoperative analgesia was infused intravenously and in group B (n=30) morphine was infused into the spinal canal. Changes in leukocyte populations and lymphocyte subpopulations in peripheral blood and blood from surgical drains (local) were analyzed to study immune cell response to morphine administration. Cortisol, corticotropin, growth hormone, glucose, and immunoglobulin levels in peripheral blood were measured as indicators of metabolic and humoral immune responses. RESULTS: Both groups developed lymphopenia in peripheral blood. The group treated with spinal morphine had significantly lower CD4+ cell counts in peripheral blood P<0.05. No differences were found in the local leukocyte response in either group. Significant differences were found in natural killer and CD4+ cell counts both locally and in peripheral blood P<0.05. There was humoral immune response suppression in both groups; however, it was more marked in the group treated with spinal morphine and the difference was significant P<0.05. The metabolic response was greater in the group treated with intravenous morphine. CONCLUSION: Patients who received morphine by spinal infusion had a less marked endocrine-metabolic response. Although local cell responses were similar in the 2 groups, the response in peripheral blood was different, possibly reflecting different mechanisms of central modulation of the inflammatory response to stress.
Adrenocorticotropic Hormone↗
[Comparison of 4 techniques for general anesthesia for carotid endarterectomy: inflammatory response, cardiocirculatory complications, and postoperative analgesia].
OBJECTIVE: [corrected] To study the analgesia, hemodynamic stability and inflammatory response in patients undergoing carotid endarterectomy under different types of general anesthesia. MATERIALS AND METHODS: A comparison of 80 patients randomized to 4 groups: group 1, maintenance with sevoflurane at a minimum alveolar concentration (MAC) of 1; group 2, sevoflurane at MAC 1.5; group 3, remifentanil; group 4, propofol. Variables studied were hemodynamic alterations during and after surgery, level of postoperative analgesia, differential white cell counts, levels of interleukin-6 (IL-6), and clinical signs and symptoms of systemic inflammatory response syndrome in the first 24 hours after surgery. RESULTS: The incidences of episodes of intraoperative hypertension were 60% in group 1, 65% in group 2, 50% in group 3, and 60% in group 4. The incidences of episodes of intraoperative hypotension were 85% in group 1, 80% in group 2, 80% in group 3, and 75% in group 4. Patients in groups 3 and 4 had higher incidences of systemic inflammatory response syndrome (p<0.05) in the first 24 hours after surgery and higher levels of IL-6 (p<0.05). Postoperative analgesia was similar in all 4 groups. CONCLUSIONS: Increased levels of IL-6 in peripheral blood and of systemic inflammatory response syndrome were found in the early postoperative period in groups that did not receive halogenated gases. Hemodynamic stability and analgesia were similar in all groups, however.
Aged↗
[HYPNOS and Revista Española de Anestesiología y Reanimación, history of a coexistence relationship].
The year 2003 will mark the fiftieth anniversary of the publication of Revista Española de Anestesiología y Reanimación (Spanish Journal of Anesthesiology and Postoperative Recovery). For that reason, it is appropriate to explore some of the details of the journal's early history. In 1954 and 1955 two official journals of anesthesiology co-existed in Spain: Revista Española de Anestesiología, which was the official organ of the Spanish Society of Anesthesiology and Postoperative Recovery, and Hypnos, which was the bulletin of the Association of Anesthesia of the Academy of Medical Sciences of Barcelona. The two publications merged in 1956 as Revista Española de Anestesiología, thereby forming the journal whose name eventually became Revista Española de Anestesiología y Reanimación.
Anesthesia↗
[Two cases of acute pulmonary edema secondary to laryngospasm].
We report two cases of acute pulmonary edema attributable to episodes of postextubation laryngospasm appearing when two young patients awoke after appendectomies under general anesthesia. Both patients improved in less than 48 hours with diuretics, oxygen therapy and liquid restriction, making tracheal intubation unnecessary. The pathophysiology and clinical and radiological signs of pulmonary edema are reviewed.
Adult↗
[Intubation according to the Gorback technique in a case of hypertrophy of the coronoid apophysis].
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Aged↗
[Brugada syndrome and anesthesia. Apropos of a case].
We describe a patient with a tentative diagnosis of Brugada syndrome who was given general anesthesia without complications. We review the main characteristics of Brugada syndrome.
Anesthesia, Inhalation↗