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Biomedical subjects

J M Aronchick

Publications and source records attributed to J M Aronchick.

28 records · Page 2Linked to original sources

Chronic beryllium disease: diagnosis, radiographic findings, and correlation with pulmonary function tests.

Patients with suspected chronic beryllium disease underwent bronchoscopy and bronchoalveolar lavage. Their bronchoalveolar lymphocytes were incubated with beryllium salts, and quantitative lymphocyte transformation was measured. Seventeen patients with a positive lymphocyte proliferation test were evaluated radiographically with the International Labour Office classification. The most common radiographic abnormalities included diffuse small round and reticular opacities. Hilar adenopathy, linear scars, lung distortion, bullae, and pleural thickening were found less commonly. Specific radiographic findings were compared with pulmonary function abnormalities. The extent of radiographic profusion of small opacities and the presence of linear scars did not correlate with pulmonary function abnormalities. There was, however, a significant correlation between extensive pleural disease and reduced vital capacity in this small group of patients.

Adult↗

Observer variation in the detection of osteopenia.

In order to determine observer variation in the detection of osteopenia, 15 pairs of lateral chest radiographs obtained within two weeks of each other were reviewed separately by two radiologists and one orthopedist on three separate occasions. Intra- and interobserver variations were calculated for each individual film and film pairs using Kappa values. The individual observers were not able to give consistent readings on the same film on different days (average Kappa = 0.54). When the additional factors of repeat films (average kappa = 0.47), or separate observers (average Kappa = 0.38) were analyzed, agreement was even worse. The identification of osteopenia from the lateral view of the thoracic spine is highly subjective and variable from film to film and observer to observer.

Humans↗

Nonlymphomatous lymphoid disorders of the lung.

Nonlymphomatous lymphoid disorders of the lung consist of several entities with varied histology and clinical behavior. On the basis of histologic appearance, six lesions can be identified. They include Castleman's disease, plasma-cell granuloma, pseudolymphoma, lymphocytic interstitial pneumonitis, angioimmunoblastic lymphadenopathy, and lymphomatoid granulomatosis. These conditions in 22 patients, their radiologic and histopathologic features, and their relationship to the malignant lymphomas are discussed. Although a radiographic diagnosis may be suggested, overlapping features mandate open-lung biopsy in most instances. The frequent evolution toward malignant lymphoma with lymphomatoid granulomatosis and pseudolymphoma necessitates close follow-up and sometimes aggressive therapy.

Granuloma, Plasma Cell↗

The troublesome nipple shadow.

In a review of 1000 routine chest examinations, the nipple of the male or female breast was visible about 10% of the time. In 14 instances (1.4%), the reviewing radiologist thought that uncertainty of identification warranted additional films. In four of these instances, the density proved to be something other than nipple. In all other instances when a nipple shadow was identified (8.9%), follow-up was not deemed necessary for various, often somewhat subjective reasons. Thus the frequency of erroneous identification of nipples could have been higher. Certainty of nipple identification would have involved considerable cost and inconvenience in repeat examinations. In another group of 500 patients, identification of the nipple with a lead marker on all patients eliminated uncertainty and the necessity for any repeat examinations. The patients placed low cost markers at the time of disrobing. Convenience and certainty were served by this simple maneuver.

Breast↗

Paget's disease.

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Adult↗

Computed tomography of bronchial carcinoid.

Computed tomography was used to evaluate three patients with endobronchial tumors. In each case the mass showed enhancement following intravenous contrast medium administration. Each patient underwent surgical resection, and pathology showed carcinoid tumor in each case.

Aged↗