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Biomedical subjects

J M Aubert

Publications and source records attributed to J M Aubert.

10 recordsLinked to original sources
PubMed1987

Expectant management of presumed ectopic pregnancies.

Thirteen patients with presumed diagnosis of unruptured ectopic pregnancy underwent expectant management. The diagnosis was based on the criteria of clinical stability, no intrauterine gestation sac by sonogram, and falling beta subunit human chorionic gonadotropin titer. The diagnosis also was based on no gross evidence of trophoblastic tissue on sharp curettage and alteration in uterotubal anatomy at laparoscopy. In these 13 patients, titers continued to drop and were below assay detectability (1.5 miu/ml) by 1 to 5 weeks. Only one patient required a laparotomy. Hysterosalpingograms in ten of the patients showed normal, patent tubes in seven. One patient had cornual occlusion and two showed a hydrosalpinx with spillage. A second laparoscopy in seven patients demonstrated normal tubes in all but one. At present, three patients have delivered term infants and two have had first trimester spontaneous abortions. These observations suggest that expectant management of tubal pregnancies is appropriate under rigidly controlled conditions.

Adolescent↗
PubMed1987

Improving Falope-Ring application in laparoscopy training.

Laparoscopic Falope-Ring sterilization was performed by residents on 71 women. Immediately following application of the ring, methylene blue was injected through the cervix to assess tubal patency. Unilateral spillage of the dye was demonstrated in four patients (5.6%). In these instances a new ring was applied, or the tube was tied surgically. The high rate of tubal patency was attributed to the surgeons' inexperience. The findings suggest that the use of a patency test as an adjunct to sterilization with the Falope-Ring in training programs is likely to decrease the rate of surgical failures.

Fallopian Tube Patency Tests↗
PubMed1983

Tetanus complicating elective surgery. Two cases following female sterilization.

Two cases of fatal tetanus infection after female sterilization are presented. The possible sources of infection are discussed and the methods for prevention are evaluated. Active immunization before surgery is the ideal method; voluntary sterilization clinics could promote tetanus immunization and contribute to the improvement of the health of the population served.

Adult↗
PubMed1982

Treatment of vaginal trichomoniasis. Single, 2-gram dose of metronidazole as compared with a seven-day course.

Although a single, 2-gm dose of metronidazole has been approved for the treatment of vaginal trichomoniasis, this regimen has not gained general acceptance. We compared the single, 2-gm dose versus the regimen of 250 mg administered three times daily for seven days. Two hundred sixty-three women with vaginal trichomoniasis were treated. One hundred seventy returned for follow-up. Of them, 96 received the single, 2-gm dose and 74 the seven-day treatment. The cure rates were 93.8% and 97.3%, respectively, and were not significantly different. These data compare favorably with those from previous studies. The side effects were minimal and occurred with greater frequency in the group receiving the single, 2-gm dose; nevertheless, the difference was not significant. We recommend the 2-gm regimen for the treatment of vaginal trichomoniasis because of its easy administration, better patient compliance and lower cost.

Drug Administration Schedule↗
PubMed1981

Five year clinical experience with the Copper 7 intrauterine device.

The clinical observation of 1547 patients who had a Copper 7 IUD inserted in a municipal hospital in New York City during the period August 1, 1974 to July 31, 1979, is presented. Despite the extreme mobility of this lower socio-economic population, complete followup was possible for 79% of the insertions. The demographic characteristics of the patients are presented, as well as the number of events and closures for the first segment of use and for all segments. The events are analyzed by patient's age, gravidity, parity and duration of use. Net annual rates for accidental pregnancies, expulsions and removals, as well as continuation rates are presented for the first 3 years of use. Net cumulative rates for the same events are presented for the 5 years of the study.

Adolescent↗
PubMed1980

Mortality risk associated with female sterilization.

The mortality risk associated with female sterilization in an analysis of 255 812 procedures performed in developing countries from 1973 to 1979 is reviewed. Fifteen sterilization-related deaths were reported during this period. The overall mortality was 5.86/100 000 procedures. The most common cause of death was the result of anesthetic complications, with infection in second place. The risk of death by procedure was higher with culdoscopy than with minilaparotomy or laparoscopy. The authors believe that low mortality figures are realistic and can be achieved in developing countries when experienced surgical teams are provided with adequate facilities, observe strict medical standards, utilize minilaparotomy and laparoscopy and avoid general and spinal anesthesia.

Adult↗
PubMed1980

Actinomyces in the endometrium of IUD users.

The colonization of the female genital tract with Actinomyces is closely related to the presence of an IUD in the uterine cavity. This was confirmed in the present study, which shows an Actinomyces frequency of over 3% in users of IUDs, while non-users were free from the opportunistic invader. This frequency was higher with certain types of devices than with others. None of the patients with positive results had pelvic symptoms, but cases of serious infections have been reported in the literature. The length of IUD usage appears to be directly related to the incidence of this colonization. The possible pathogenesis of pelvic actinomycosis is presented; the clinical significance of asymptomatic colonization is discussed.

Actinomyces↗
PubMed1980

Incidence of hyperprolactinemia during oral contraceptive therapy.

A study was undertaken to determine the incidence of increased serum levels of human prolactin (hPRL) in women during oral contraceptive therapy, and to correlate this with both the dose of oral contraceptive medication and the duration of its use. The 123 patients in this study were divided into 3 groups according to the dosage of estrogenic component of the combined oral contraceptives. Thirty percent of these women had hyperprolactinemia of varying degree. Neither the dosage of steroids within our range nor the duration of therapy correlated with the presence or degree of hyperprolactinemia. The actions of estrogen-progestin compounds on hPRL are discussed.

Adolescent↗
PubMed1979

Serum prolactin levels in short-term and long-term use of inert plastic and copper intrauterine devices.

Serum prolactin values were assessed in 59 normally menstruating parous women; groups were divided with respect to short-term (6 weeks) and long-term (4-60 months) use of either the inert plastic IUD (Saf-T-Coil or Lippes Loop) or copper IUD (Cu-7). Preinsertion values served as controls in the short-term study while a separate control group using barrier contraception was used in the long-term study. Prospective analysis of short-term IUD use and retrospective analysis of long-term IUD use revealed no significant differences in mean hPRL compared to control values. Both short- and long-term mean values were within the normal range for serum hPRL. In addition, duration of use had no significant effect on hPRL values.

Adolescent↗