Re: giant leg ulcer in Wegener's granulomatosis treated with plasmapheresis and skin graft.
Explore the source record for details and available documents.
Diagnosis, Differential↗
Biomedical subjects
J M Barros
Publications and source records attributed to J M Barros.
[PSA and hormone-refractory period in prostatic cancer].
Study of the characteristics of the hormone-refractory period in 32 patients with disseminated prostate cancer who had achieved a complete response to total androgen suppression, appreciating in all of them a subclinical or asymptomatic stage and a clinical or symptomatic one. The subclinical stage was characterized by raised PSA levels and ranged between 3-35 months; at 12 months 59% of patients had advanced to the symptomatic stage, while at 24 months this percentage is 84%. The clinical stage extends from appearance of symptoms to the patient's death, ranging from 3 to 32 months; at 12 months 41% has died; and 91% at 2 years.
Adenocarcinoma↗
[Wünderlich syndrome caused by metastatic gastric sarcoma in the kidney. Report of a case].
Contribution of one case of Wünderlich Syndrome secondary to a simple metastasis to the right kidney from a gastric sarcoma operated three years earlier. Pain, palpable mass on the side and decreased haematocrit were the primary symptoms. Diagnosis was confirmed by Computerized Axial Tomography. The therapeutical approach was radical nephrectomy. At 5 years, this female patient remains alive showing no evidence of tumoral disease in the follow-up controls performed.
Aged↗
[Polypoid cystitis mimicking bladder tumor].
Presentation of one case of polypoid cystitis in a 38 year-old male, with no urological history. The form of clinic presentation and the endoscopic exploration induced to suspect the existence of a bladder tumour. Diagnosis was confirmed by the result of the histopathological study of the piece.
Adult↗
[Controversies and progress in the diagnosis and treatment of benign prostatic hypertrophy. Personal experience].
Historically, non surgical procedures awakened little interest among urologists because surgery represented a definite solution with acceptable morbidity and mortality rates. Currently, the diagnosis and management of BPH is pointed towards a greater understanding of those prostate conditions with a trend to obstruction, using more refined methods to assess the severity of the obstruction, identification of predictive parameters of the therapeutical response, and evaluation of the various treatment alternatives based on safety and cost-efficiency parameters.
Humans↗
[Acute scrotum as clinical presentation form of testicular tumor].
Testis tumours usually emerge in young patients as a painless increase in the testis size accidentally noticed by the patient. Contribution of one case of non-seminomatous testis tumour which presented clinically as an acute scrotum. An exhaustive appraisal of the clinical data allowed to choose the most appropriate approach for the patient in an emergency situation.
Acute Disease↗
[Inverted papilloma of the urethra].
The inverted papilloma of the urethra is an exceptional entity. It occurs as a smooth surface, sessile tumour located in the prostatic urethra. Microscopically, it is lined with transitional epithelium which is projected inside the tumour, creating strands of cells with normal characteristics. All cases reported up to now have occurred in men aged between 49 and 79. None of the cases had additional urothelial injuries associated. Contribution of a new case of inverted papilloma of the prostatic urethra in a 52-year old male. Transurethral resection of the tumour was the procedure chosen. Evolution was good and no relapse nor further urothelial injuries were observed at the controls carried out over an 8-year follow-up period.
Humans↗
[Renal leiomyosarcoma].
Presentation of one case of a large, rapidly growing and highly aggressive renal leiomyosarcoma. The diagnostic and therapeutical possibilities of this infrequent tumour are analyzed.
Aged↗
[Non-chromaffin non-functioning aortosympathetic paraganglioma].
The paraganglia system is the largest component in the construction of the Disseminated Neuroendocrine System, comprising cells derived from the neural crest, with ability to synthesize and secrete catecholamines, hormones and peptides. A general explanation on the subject with a personal contribution is made.
Adult↗
[Results of treatment with interferon and vinblastine in renal cancer].
Contribution of our experience with Alpha-2a Interferon and Vinblastine, for the treatment of advanced renal cancer in patients formerly not treated with nephrectomy. Pathoanatomical diagnosis was confirmed by puncture biopsy. None of the 4 patients recruited in the protocol showed objective response. In 2 patients no change was observed and in the other 2 the disease progressed. In surviving patients it was impossible to sustain therapy for more than three months. Treatment was discontinued as a result of the Interferon side-effects, such as fever, myalgia, asthenia and neuritis.
Biopsy, Needle↗
Bilateral abscessed orchiepididymitis associated with sepsis caused by Veillonella parvula and Clostridium perfringens: case report and review of the literature.
Veillonella species is a gram-negative coccus which is part of the anaerobic normal flora in the oral cavity, small intestine, upper respiratory tract, vagina, and urinary tract. The role that this organism plays in infection is not well known, and it is generally associated with other bacteria. We present a case of bilateral abscessed orchiepididymitis associated with septicemia due to Veillonella parvula and, later, to Clostridium perfringens, with the development of severe renal insufficiency and septic shock, which resolved favorably with antibiotic therapy, treatment of shock, and hyperbaric oxygen therapy. In reviewing the literature, we have not found any other case of sepsis due to Veillonella sp. associated with urological disorders.
Abscess↗
[Prospective studies for determining the duration of prevention in superficial tumors of the bladder].
The study covers a series of 221 patients with pTa or pT1 vesical tumours who were treated by RTU and had an endovesical cytostatic agent instilled prophylactically for a year. Before beginning the tumour resection, biopsies in map with cold forceps were routinely taken from the trigone, side walls, bottom walls and vesical cup. It was decided to monitor the patients by performing cystoscopies and biopsies in map with cold forceps every quarter. During the second and third year the endoscopic and bioptic monitoring was done every six months. During the time when the cytostatic agents were instilled, a significant decrease (p less than 0.01) in the percentage of patients with 'CIS' was observed. After discontinuing the instillation, the percentage of patients with 'CIS' reversed to similar figures as seen prior to the study. It can be deduced from this observation that prophylaxis can be effective against those elements of the urothelial disease which influence the arrival of new events and the increase of the tumoral stage, and that the control of those factors disappears when the prophylaxis is discontinued. The study illustrates that prophylaxis in the urothelial disease should be maintained indefinitely.
Administration, Intravesical↗
[Report of the Study Commission on Leprosy Control in the State of São Paulo].
Explore the source record for details and available documents.
Brazil↗
[Toxicity of prophylaxis of superficial bladder tumors].
The paper reviews the various prophylaxis modalities in surface vesical tumours in order to define the degree of toxicity caused by each of them. Also, a prophylaxis diagram is prepared, having into account each substance's toxicity, the benefit awarded to each of then and the tumour prognosis. The agents under assessment are Thiotepa, Adriamycin, Epirubicin, Cisplatin, oral Methotrexate, Mitomycin-C, Mitoxantrone, Interferon and BCG, at doses of 40, 120 and 150 mg. Two groups of prophylactic agents can be identified with regard to toxicity. The first one is constituted by Interferon, Adriamycin, Epirubicin and Mitomycin-C, with side-effects lower than or close to the net benefit estimated for each. The second group comprises cytostatic and immunomodulatory compounds with toxic effects greater than their net benefit. In this group, three different situations can be distinguished: a) BCG with high toxicity and high net benefit; b) Cisplatin, Thiotepa and Mitoxantrone with high toxicity and net benefit similar to that of Adriamycin, Epirubicin and Mitomycin C; and c) Oral Methotrexate, with high toxicity and no benefit. According to their toxicity levels, Interferon, Adriamycin, Epirubicin and Mitomycin C are indicated in the prophylaxis of medium-risk tumours, while BCG only in high-risk tumours. Thiotepa, Cisplatin, Mitoxantrone and oral Methotrexate have to be eliminated due to their negative benefit-toxicity relationship.
Antineoplastic Agents↗