PubMed HealthSearch

Biomedical subjects

J M Beal

Publications and source records attributed to J M Beal.

At least 19 recordsLinked to original sources

Choledocholithiasis associated with acute cholecystitis.

A retrospective review of the records of 1,507 patients with a diagnosis of cholecystitis was conducted for the five-year period, 1972 to 1977. Of this group of patients, a histopathologic diagnosis of acute cholecystitis was established in 154 patients (10.2%). Common duct calculi were detected in 17 of these 154 patients, an incidence of 11%. Preoperative evaluation by means of serum bilirubin and alkaline phosphatase levels and intravenous cholangiography was unsatisfactory for consistent demonstration of choledocholithiasis in the presence of acute cholecystitis. Intraoperative cholangiography was found to be the most reliable method for detection of common duct calculi and was successfully employed in 14 of 17 patients with choledocholithiasis. The remaining three patients had palpable stones.

Acute Disease

Lipoma of the colon.

Lipoma, an uncommon tumor in the gastrointestinal tract, occurs most often in the colon. The majority are asymptomatic but may cause abdominal pain, obstruction, or bleeding. The diagnosis can be made roentgenographically but is usually not made until operation is performed. Small lipomas may be removed by colonoscopy or followed conservatively after biopsy via colonoscopy. The treatment for symptomatic or large lipomas is surgical excision.

Aged

Obturator hernia: an elusive diagnosis.

Obturator hernia is an uncommon problem that occurs predominantly in elderly, debilitated women. The diagnosis should be suspected in such patients who have evidence of small bowel obstruction, often initially intermittent, and who complain of pain along the anteromedial aspect of the thigh. We present experience with three patients that characterizes the difficulties in diagnosis and treatment. Most patients require resection of the incarcerated bowel. Mortality is variable and is related to the condition of the patient.

Age Factors

Biliary bacteria and hepatic histopathologic changes in gallstone disease.

This study attempts to assess the frequency and severity of liver damage in patients with gallstone disease and the role of bacteria in the development of these changes. Needle biopsy of the liver demonstrated acute inflammation of portal triads in 19 of 126 patients with gallstones, a finding not present in control patients. Acute inflammation occurred more often in patients with acute cholecystitis and choledocholithiasis than in chronic cholecystitis. Cultures of the biliary tract or liver were positive in 23 of 64 patients. The frequency of positive bile cultures increased with the severity of the biliary tract disease. Five out of 6 positive liver cultures were from patients with acute cholecystitis or choledocholithiasis. The data suggest that impairment of bile flow is responsible for the acute hepatic inflammatory changes.

Adolescent

A study of polybutilate lubricated polyester sutures.

In the 49 patients in whom polybutilate coated polyester sutures were used, no adverse side-effects, such as increased redness, tenderness, pain or edema of the wounds, were noted. Primary healing was achieved in each patient. There were no suture related complications encountered during the early or late follow-up examinations. Polybutilate coated polyester sutures were found to be easy to work with. They were strong, pliable and handled and tied with ease. They had no tendency to twist, tangle or adhere to gloves or instruments. Tissue passage through skin, fascia, arteries, veins and Dacron vascular grafts was better than it was with uncoated polyester sutures and as good as with Teflon coated sutures. No unusual drag, pull or catching of the sutures was encountered. Over-all, the polybutilate coated polyester suture is thought to be a safe, reliable and an easy to use material for a wide variety of surgical procedures for which a strong nonabsorbable suture is indicated.

Adolescent

Villous adenoma of the duodenum. A case report and review of the literature.

A case of villous adenoma of the duodenum, with focal in situ carcinomatous changes, has been described with a review of forty-two other case reports from the world literature. Occult bleeding, resulting in anemia, and vague obstructive symptoms appear to be the most common presenting findings. The average age was 56.4 years, which was seven years younger than the average age for villous tumors of the colon. Adequate radiologic studies should establish the diagnosis preoperatively. These tumors obtain relatively large size before causing significant symptoms. Approximately one third showed carcinomatous changes, and approximately one half of these were in situ changes. Local segmental resection for duodenal villous tumors is desirable when possible. However, in areas where this is not feasible, local mucosal excision is acceptable for benign tumors and for those with in situ carcinoma. If invasive carcinoma is found in the excised specimen, pancreatoduodenectomy is recommended. Insufficient evidence is available to adequately evaluate survival for malignant villous tumors of the duodenum, but the available data suggest that the survival after treatment of malignant villous tumors is comparable to other malignant lesions originating in the duodenum.

Adenoma