Experimental lathyrism in the South African toad.
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Biomedical subjects
Publications and source records attributed to J M CAMERON.
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Determinations were carried out of the ABO blood groups and Rhesus phenotypes of a series of 142 children with Perthes' disease. Where possible their parents and sibs were also grouped. Sera from the mothers of affected children were examined for the presence of Rhesus antibodies. No apparent association was demonstrated between Perthes' disease and any ABO phenotype. The disease is also apparently independent of ABO incompatibility between mother and child. There is the suggestion in these families of an increased incidence of the Rhesus cc phenotype among the affected children. The level of significance is estimated at 0.02, even after taking into account the numerous significance tests possible on the data. Parental and sibship studies show that any association between Perthes' disease and the Rhesus Cc phenotypes, if one does exist, is unlikely to be the product of genetical stratification within the population. Maternal Rhesus antibody, acting through the agency of haemolytic disease of the newborn, plays no detectable part in the aetiology of a subsequently developing Perthes' disease in the child.
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A clinical study of 401 cases of tumour of salivary tissue has been made and the results reported, together with a review of the literature. The histological variations of such tumours are classified and discussed.
During the past 11 years almost 4,000 necropsies have been performed at the Southern General Hospital, Glasgow, and of these, 924 showed malignancy of which 45 were of primary carcinoma multiplex. Two cases showed triple and one quadruple malignancy, and the remainder two primary malignant tumours.
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