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Biomedical subjects

J M Cabezudo

Publications and source records attributed to J M Cabezudo.

At least 19 recordsLinked to original sources
PubMed1992

Focal dystonia secondary to cavernous angioma of the basal ganglia: case report and review of the literature.

The case of a young woman with focal dystonia of the hand due to a cavernous angioma of the basal ganglia is presented. The lesion involved the anterior third of the lentiform nucleus and a large portion of white matter anterior to this nucleus and lateral to the head of the caudate, as shown by magnetic resonance imaging; it was completely removed through a computed tomography-assisted stereotactic craniotomy by microsurgical technique, resulting in the cure of the patient. These facts support the pathophysiological hypothesis of a disruption of the striatopallidothalamic projection to the premotor cortex as the cause of symptomatic dystonia. A review of the reported cases of cavernous angiomas of the deep cerebral gray nuclei shows that this is the first case of cavernous angioma associated with movement disorder.

Adult↗
PubMed1986

Recovery from locked-in syndrome after posttraumatic bilateral distal vertebral artery occlusion.

A 55-year-old man developed a delayed locked-in syndrome after a mild head injury. Angiography showed bilateral distal vertebral artery occlusion. Anticoagulant therapy and energetic medical management to promote collateral circulation to the structures in the posterior fossa led to a functional recovery. A review of the reported cases of posttraumatic locked-in syndrome has allowed the authors to differentiate between two types: the first is due to primary brainstem injury and the second is due to secondary brainstem ischemia. Both types have different modes of onset, mechanisms of production, angiographic findings, and prognosis. It is concluded that, with early diagnosis and vigorous medical management, expectations for a useful recovery are high, especially in those cases of posttraumatic locked-in syndrome due to secondary brainstem ischemia.

Adult↗
PubMed1985

Symptomatic root compression by a free fat transplant after hemilaminectomy. Case report.

The authors report a case in which a free fat graft, placed at the operative site after hemilaminectomy for lumbar disc herniation, was forced into the spinal canal by action of the paraspinal muscles and behaved as a symptomatic space-occupying lesion. The patient recovered satisfactorily after the graft was removed. The pathogenetic mechanism is discussed and guidelines to avoid this complication are outlined.

Adipose Tissue↗
PubMed1983

Cystic cavernous haemangiomas of the brain.

Two cases of cystic cavernous haemangioma of the brain are reported. In both cases, an erroneous diagnosis of cystic glioma was made, because of the unusual CT scan findings. Cavernous haemangiomas should be included in the differential diagnosis of intracranial cystic lesions.

Adult↗
PubMed1982

Subjective postoperative results in cervical spondylotic myelopathy.

A retrospective study of operative results after a minimum follow-up period of five years was carried out in a series of 34 patients operated upon for cervical spondylotic myelopathy (CSM). In all the cases, myelography showed involvement of two or more intervertebral spaces. Constitutional spinal cord narrowing was not present, and only one operation was performed in each patient. Of the 34 patients, 16 also had symptoms of cervical spondylotic radiculopathy (CSR). Seventy-four percent of the patients thought that operation resulted in overall improvement of the preoperative clinical picture. This subjective improvement was similar whether the operative procedure consisted of anterior intersomatic fusion or of laminectomy. Amelioration of CSM symptoms occurred in only 8 of the 20 patients subjected to anterior fusion (40%), in contrast to 10 of the 14 patients subjected to laminectomy (71%). In the 16 patients with CSR symptoms associated with CSM, amelioration of CSR symptoms occurred in 6 of the 11 patients subjected to anterior fusion (55%), and in 4 of the 5 patients subjected to laminectomy 80%). It is suggested that laminectomy offers the best results for CSM, associated or not with CSR, when two or more intervertebral spaces are affected.

Adult↗
PubMed1982

Morphological study of human epileptic dendrites.

We studied 14 human epileptogenic foci with light and electron microscopy to establish their morphological patterns. Using silver staining techniques, we found dendritic areas devoid of spines, dendritic angulations, and nodular or segmentary dendritic swellings. When these findings were compared with the morphology of nonepileptic cortex, only the existence of dendritic swellings in the epileptic tissue was significant. Electron microscopy showed that the nodular dendritic swellings were due to an alteration in the normal arrangement of the microtubules. We hypothesize that an alteration in the microtubular arrangement causes a mechanical distortion of the dendritic membrane and subsequently may cause its depolarization.

Dendrites↗
PubMed1981

Meningioma of the anterior part of the third ventricle.

The authors report the clinical features, radiological findings, and surgical management in a case of meningioma of the anterior part of the third ventricle in a 59-year-old woman. The unusual fact in our patient compared with the other reported cases is that she never developed symptoms or signs of increased intracranial pressure. A review of the literature is presented. Ours is the second case in which CT scan has been used in the diagnosis.

Cerebral Ventricle Neoplasms↗
PubMed1981

Ependymal reaction after experimental spinal cord injury.

Images of ependymal cell proliferation after experimental spinal cord injury in the rabbit are presented. This finding suggests that segmental central canal obliteration after injury could be considered in the pathogenesis of posttraumatic syringomyelia.

Animals↗