[Antidepressive agents and anxiety].
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Biomedical subjects
Publications and source records attributed to J M Chignon.
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The numerous recent trials devoted to disruptive behavior disorders indicate the renewed interest of clinicians for these so-called dimensions and call for revision of the instruments with which they are evaluated. The present paper provides a brief review of the currently used scales for rating impulsivity. A new scale for evaluating the behavioural dyscontrol is proposed. The items of this scale are selected a priori according to clinical experience with patients suffering from lack of behavioural control. The Behaviour Dyscontrol Scale (BDS) includes, in the initial version, 4 parts. The first part concerns the generalized lack of control (G-BDS). This is a questionnaire of 24 items. The second part is constituted by a questionnaire which lists a number of specific behaviours where impulsivity has a central role (S-BDS). Part III is constituted with 4 Visual Analogue Scales for evaluating handicap linked to dyscontrol. Part IV is constituted by 3 Visual Analogue Scales concerning the physician global impression about the lack of general control in cognitions, emotions and behaviours. For validation, 166 patients (111 females and 55 males), either hospitalized or ambulatory, and 35 controls (16 females and 19 males) were included in this study. Mean age of patients was 38.5 (SD = 10.5) years. The patients population is subdivided in 4 subgroups, anxious, depressed, abusers and bulimics according to DSM III-R criteria. Patients and controls global scores were significantly different at the G-BDS (p less than 10(-4)) and not at S-BDS.(ABSTRACT TRUNCATED AT 250 WORDS)
Relationships between alcoholism and anxiety disorder are well known by clinicians. Studies have recently shown that the prevalence of alcohol abuse or dependence is very high in patients with panic disorder with or without agoraphobia (Thyer et al., 1986; Bibb and Chambless, 1986). The aims of this study were to determine the prevalence and comorbidity of alcohol abuse and dependence in a population of panic outpatients who were consecutive referrals for treatment of panic disorder (PD) in an anxiety clinic. Patients were interviewed with the Schedule for Affective Disorders and Schizophrenia-Lifetime Version Modified for the study of anxiety disorders (SADS-LA) which is a standardized and semi-structured interview allowing to make diagnoses according to RDC, DSM III and DSM III-R criteria. One hundred and three panic patients (39 males and 64 females) were included in the study. Their mean age was 38.5 years (SD: 11.6). In this sample, 24.3% met the DSM III-R criteria for alcohol abuse and 8.7% those for alcohol dependence. Among these patients, 26.2%, abused of benzodiazepines and 16.5% of them of other substances. We found a high comorbidity rate. In fact, 6.8% of the patients met diagnostic criteria for PD alone, 31.0% for one more diagnosis, 29.1% for two more and 33.0% for three or more besides PD. In this study, we found an association between alcohol abuse and the presence of a lifetime diagnosis of major depressive episode and/or other addictive behaviors. Otherwise, alcohol abuse did not occur more often in patients suffering from panic disorder associated with agoraphobia and/or social phobia.