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Biomedical subjects

J M Coke

Publications and source records attributed to J M Coke.

At least 19 recordsLinked to original sources
PubMed2000

Acute porphyric disorders.

Acute porphyrias are classified into 3 distinct groups of rare genetic disorders of metabolic enzyme biosynthesis. Acute porphyrias can significantly impact multiple organ systems, which often provides a challenge to the dentist presented with such a patient. A case of hereditary coproporphyria is reported in a patient with many of the classical signs and symptoms. The patient also had complex dental needs that required special medical and pharmacotherapeutic modifications. The acute porphyrias are reviewed by the authors with presentation of this challenging case. Recommendations for other dental health care professionals encountering these patients are then presented.

Acute Disease↗
PubMed1987

Midazolam, diazepam, and placebo as intravenous sedatives for dental surgery.

This study was a comparison of the sedative and amnestic properties of midazolam and diazepam when administered for relief of patient discomfort during dental surgery. It was a double-blind placebo-controlled group study, which entailed the analysis of 60 patients randomly assigned to the three groups: midazolam, diazepam, and placebo. There were 20 patients in each group. Midazolam patients showed superior performance in the parameters of sedation and amnesia when compared to patients who were administered diazepam. Both groups showed better results than the placebo group, which had the best results with the Digit Symbol Substitution Test and the Trieger Test.

Adolescent↗
PubMed1980

Intramuscular sedation technique.

A sedative technique with meperidine hydrochloride and promethazine hydrochloride via an intramuscular injection is presented. We believe this is an excellent technique because of the safety to the patient and the ease of administration. Like any technique using potentially dangerous medications, practitioners and their staff must be familiar with and prepared for possible complications. When the technique is mastered, it will be a valuable addition for treatment of certain mentally and physically handicapped patients.

Anesthesia, Dental↗
PubMed1979

Complications related to the administration of general anesthesia in 600 developmentally disabled dental patients.

A total of 600 handicapped patients had dental rehabilitation under general anesthesia during an eight-year period. Handicaps included mental retardation, cerebral palsy, Down syndrome, seizure disorders, autism, cystic fibrosis, osteogenesis imperfecta, and muscular dystrophy. No significant complications developed in the majority of patients. This is attributed to thorough preoperative evaluation, appropriate anesthetic management, and vigilant postoperative observation.

Adolescent↗
PubMedDate not supplied

Treatment modalities for intraoral Kaposi's sarcoma: report of case.

Intraoral Kaposi's sarcoma (KS) is a lesion seen commonly in patients with AIDS. These lesions can interfere with both speech and mastication. The dental team should be aware of the various treatment modalities for KS and the complications associated with these treatments. One of the treatment modalities reviewed here can be safely administered in a dental office.

Acquired Immunodeficiency Syndrome↗