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Biomedical subjects

J M Corboy

Publications and source records attributed to J M Corboy.

15 recordsLinked to original sources

Postanesthetic hypotropia: a unique syndrome in left eyes.

PURPOSE: To investigate a recurring syndrome of postoperative hypotropia after cataract surgery performed under local anesthesia. SETTING: Hawaiian Eye Center, Wahiawa, Hawaii, USA. METHODS: Thirty-one left eyes in 2143 cataract surgeries developed postoperative hypotropia. Phacoemulsification and intraocular lens implantation were performed by one surgeon; the anesthetic (containing bupivacaine) was administered by one anesthesiologist who had treated 4200 patients without incident. We conducted epidemiologic, outcomes, and prevention studies to identify the etiology, evaluate hypotropia treatment, and test specific anesthetic techniques, respectively. RESULTS: Changes in preoperative and intraoperative management and surgical methods were unsuccessful in preventing the hypotropia. In 55% of the cases, strabismus surgery was required and in 13%, prism glasses. Early recession of the inferior rectus and conjunctiva was successful. After repeated observations of the anesthetic technique, it was noted that the right-handed anesthesiologist misdirected the retrobulbar needle into the left orbit. This resulted in a change in the anesthetic technique, and there has been no incidence of postoperative hypotropia in 3000 surgeries. CONCLUSION: We believe this syndrome resulted from mytoxicity or perimuscular inflammation, producing contracture hypotropia and restricted elevation of the globe. We propose the term postbupivacaine hypotropia for this chiefly left-sided syndrome.

Anesthesia, Local↗

Rabies prevention in Hawaii.

The scientific basis of Hawaii's public health rabies prevention program is discussed, as is a proposed minor modification offered to assist Hawaii residents who use guide dogs and who want to travel out of state. Hawaii's current quarantine program has successfully prevented the introduction of the disease. Alternative programs involve risks that are not easily evaluated.

Animals↗

Neodymium: YAG laser capsulotomy with a biconvex intraocular lens.

There are optical and mechanical advantages of the biconvex posterior chamber intraocular lens (IOL) following cataract surgery. A clinical study of Nd:YAG laser capsulotomy in eyes with biconvex IOLs was undertaken. The lenses were made of injection-molded poly(methyl methacrylate) without laser spacing. Using specified techniques, YAG laser capsulotomy was performed in 19% of 436 eyes without significant damage to the IOL and without affecting visual acuity or glare disability.

Cataract Extraction↗

Outpatient surgery.

Explore the source record for details and available documents.

Ambulatory Surgical Procedures↗

Nitrous oxide analgesia for outpatient surgery.

Nitrous oxide analgesia was used prior to local anesthesia in over 200 outpatient implants and was very effective in reducing anxiety and pain of injections. Sedation by nitrous oxide is characterized by unique absorption, distribution, and elimination, which result in rapid onset and rapid recovery. The drug is widely accepted as a nontoxic conscious sedation modality, and simple machines permit easy and safe administration. The drug is particularly desirable in the elderly who may have respiratory or cardiovascular disease, and seems ideally suited to ambulatory surgicenters.

Aged↗

Results of 100 consecutive anterior chamber implants.

Using an anterior chamber lens made from Perspex CQ we began a series of 100 consecutive implantations in 1976. Iris tucking of at least one foot of the lens was found in 19 cases, however this complication was not associated with iritis or glaucoma at the time of the study. Tenderness over the operative eye was rare and did not appear to be a significant problem. There were no cases of the uveitis-glaucoma-hyphema syndrome. For an average follow-up time of 12.3 months, 90% of the eyes without pre-existing retinal pathology demonstrated 20/40 or better visual acuity.

Adult↗

Choyce lens warp testing: effect of temperature and pressure changes.

Choyce-style lenses made from sheer PMMA (ICI Perspex CQ) have a different thermal response than lenses made of Rohm & Haas injection molded PMMA: Perspex lenses are more resistant to high temperature deformation. However, under simulated physiologic temperatures and pressures, there is no apparent lens deformation, nor is there a difference in response between lens types. In general, the susceptibility of all thermoplastics to heat, and the ease with which high temperatures may be achieved in transportation, require improved packaging; great care must be taken to protect and inspect intraocular lenses before implantation. Demonstrated variation in thermal response from lens to lens, and even from foot to foot, further mandates such care and also cautions against the acceptance of claims based on inadequate or incomplete data. All lenses should be checked, with the best clinical test for flatness being that in which each foot is depressed to check for rocking or lift.

Humans↗

Corticosteroid therapy for the reduction of postoperative inflammation after cataract extraction.

In an random, double-masked multicentric clinical trial, topical betamethasone phosphate 0.1% or placebo eyedrops were used five times daily for the first two weeks after uncomplicated intracapsular cataract extraction in 107 patients who had moderate to severe postoperative inflammation on the first postoperative day. Topical corticosteroid solution was significantly more effective than placebo in the reduction of postoperative ocular inflammation. There were no ocular complications of corticosteroid treatment.

Adrenal Cortex Hormones↗