PubMed HealthSearch

Biomedical subjects

J M Debry

Publications and source records attributed to J M Debry.

4 recordsLinked to original sources

[An evaluation of the first two years of activity at the in vitro fertilization center in the +Notre Dame Clinic in Charleroi+(Belgium)].

An in vitro fertilisation unit has been working since the 1 st May 1988 in the Notre-Dame Clinic in Charleroi in the Beligium province of Hainaut. This work analyses the practice and results of the first two years activity in which 185 oocytes retrievals were carried out. The account not only deals with the results (according to 8 criteria for evaluation) but also on the factors that modify these results (9 parameters). It is scientific tools that makes it possible to analyse objectively and precisely, the factors leading to success or failure in our technique. The results are compared with those in the literature and in the French national enquiries (these do not exist in Belgium) show that even in modest conditions (2 gynaecologists and a biologist who have other duties) it is possible to carry out in the first year 62 and in the second year 123 oocyte recoveries. The scrupulous attention to technical details in this university centre of reference made it possible from the beginning to achieve worthwhile results (21% pregnancies for all recoveries and 32% pregnancies for all embryo transfers).

Adult

[The hamster test. Practical consequences].

The result of the in vitro human sperm penetration test into hamster eggs must not be considered as absolute. It is a step in the management of male infertility and must be interpreted in regard of the results of other tests. In our experience, if the test is negative, the probability to observe a pregnancy in the patient's partner is about one in seven and half years; if the test is positive, it is about one in two and half years. On the other hand, if a pregnancy occurs, with a positive or a negative test, it will start 5 to 7 months later.

Animals

The hamster test in a series of 120 infertile patients.

The value of a test based on penetration of human sperm into zona-free hamster ova is evaluated by the authors. Rudak's technique was used in 120 infertile patients. The Authors affirm that the hamster test is at present the only practical functional test for the evaluation of the fertilizing capacity of human spermatozoa and that it will probably be more widespread in the future.

Adult