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Biomedical subjects

J M Diekmann

Publications and source records attributed to J M Diekmann.

11 recordsLinked to original sources
PubMed1991

A survey of nursing students' knowledge of cancer pain control.

The World Health Organization estimates that approximately 3.5 million people suffer daily from cancer pain. Recently, a Midwestern state was named by the World Health Organization to lead worldwide efforts in controlling the pain experienced by cancer patients. As part of this effort, the Nursing Education Committee conducted a statewide study of first year and final year nursing students from 19 nursing programs. The purpose of this study was to determine nursing students' perceptions and knowledge about cancer pain control. After the deans and directors of the nursing programs were contacted to obtain their agreement to participate, questionnaires composed of 26 items were mailed to each nursing school and distributed to students. Nine hundred thirty-eight questionnaires were returned to the researchers, realizing a 40% return rate. Data analysis reflects poor knowledge about the prevalence of cancer pain and its management. Using the student's t-test, significant differences between the scores of first year and last year students were found with last year students achieving higher mean scores. It was concluded that more information about how to manage cancer pain needs to be provided in nursing curricula. It is recommended that faculty members frequently update their knowledge and skills about cancer pain management.

Adult↗
PubMed1977

Angiotensin II-induced contractions of rabbit splenic capsular strips and release of prostaglandins. Use of radioimmunoassays for prostaglandins E1 and E2.

Rabbit splenic capsular strips contract in response to angiotensin II and simultaneously release prostaglandins E and F into the bath fluid. Contractions, though not sustained, and prostaglandin release are dependent on the concentrations of angiotensin II. Addition of indometacin to the bath fluid inhibits prostaglandin release and potentiates the angiotensin II-induced contractions. Similarly, 5,8,11,14-eicosatetraynoic acid, another blocker of prostaglandin synthesis, potentiates contractions elicited by angiotensin II. Exogenous prostaglandin E1 (300 ng/ml) tends to decrease angiotensin II-induced contractions, while prostaglandin E2 (300 ng/ml) as well as prostaglandin F2alpha (300 ng/ml) significantly increase the contractions produced by angiotensin II. The prostaglandin endoperoxide analogues (15S)-hydroxy-9alpha,11alpha-(epoxymethano)prosta-5Z,13 E-dienoic acid and (15S)-hydroxy-11alpha,9alpha-(epoxymethano)-prosta-5Z,13 E-dienoic acid in concentrations of 300 ng/ml are either without effect or weak smooth muscle stimulants of their own, but do not influence the effect of angiotensin II. By the simultaneous use of sensitive and specific radioimmunoassays for prostaglandins E1 and E2 the prostaglandin E-like substance released by the rabbit splenic capsular strips was found to resemble serologically much more the dienoic prostaglandin E2 than prostaglandin E1. The potentation of the effect of angiotensin II by indometacin and 5,8,11,14-eicosatetraynoic acid might be caused by inhibition of synthesis of prostaglandins or related compounds in the splenic tissue. However, an undefined sensitizing effect of indometacin and 5,8,11,14-eicosatetraynoic acid, not related to their effect on prostaglandin synthetase, on the smooth muscle preparation cannot be excluded.

5,8,11,14-Eicosatetraynoic Acid↗
PubMedDate not supplied

The effect of social learning intervention on metabolic control of insulin-dependent diabetes mellitus in adolescents.

This paper reports the results of an experimental study modeled after a study conducted by Kaplan et al. The hypothesis tested was: Adolescents who receive a social learning intervention (SLI) will show greater improvement in metabolic control of their diabetes than will adolescents who receive only traditional diabetes instruction. Thirty-four adolescents between the ages of 12 and 16 who attended a midwestern camp were randomly divided into two groups. Both groups attended a daily 1-hour teaching session about diabetes. Later each day, the experimental group received an SLI consisting of role modeling to help the subjects circumvent peer pressure. To determine metabolic control, HbA1 values were determined before and 3 1/2 months after the intervention. The control group showed no significant difference in HbA1 values, while the experimental group showed a decrease in metabolic control.

Adolescent↗
PubMedDate not supplied

Cancer pain control: one state's experience.

The World Health Organization estimates that approximately 3.5 million people suffer daily from cancer pain. Approximately 30% to 40% of people with intermediate stages of cancer and 55% to 90% of patients with advanced or terminal disease have pain. A multidisciplinary effort is under way in Wisconsin to improve cancer pain management. In recognition of the state's initiative, the World Health Organization has designated Wisconsin a demonstration state for cancer pain management. Support for staffing is provided by the United States Public Health Service Interagency Committee on Pain and Analgesia. In December 1986, 65 people representing 50 health organizations met to develop a comprehensive plan of action to improve pain management in people with cancer. In this article the various statewide activities focused at improving cancer pain management are discussed.

Analgesia↗