Computer software programs and Down's syndrome risk calculations.
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Algorithms↗
Biomedical subjects
J M Donhowe
Publications and source records attributed to J M Donhowe.
Laboratory evaluation of hyper- and hypoglycemic states.
Appropriate use of test strategies requires not only an appreciation of analytic considerations and the ability of the tests to confirm or exclude the hypotheses, but also an understanding of the underlying pathophysiology and clinical features of the problems to be addressed. This discussion covers disease definition, pathophysiology, analytic considerations, and strategies for diagnosis and management.
Blood Glucose↗
The effects of circumcision on serum cortisol and behavior.
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Behavior↗
Factitious hypophosphatemia related to mannitol therapy.
We observed factitious hypophosphatemia in a patient who was receiving large amounts of intravenous mannitol. Mannitol concentrations as low as 25 mmol/L inhibited phosphorus measurement by the Dupont aca endpoint method; a kinetic method was unaffected. The mechanism of the mannitol interference was binding to molybdate in the reaction, decreasing both the rate of color development and the endpoint measurement. We conclude that the molybdate concentration in the DuPont method is suboptimal for measuring phosphorus in specimens containing mannitol.
Brain Edema↗