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J M Estavoyer

Publications and source records attributed to J M Estavoyer.

63 records · Page 4Linked to original sources
PubMedDate not supplied

[Splenic infarction in Plasmodium falciparum malarial attack].

Splenic infarct during P. falciparum malaria is rare but well known. We report one case where ultrasonography and computed tomography suggested the diagnostic, showing respectively in splenic parenchyma a peripheral hypoechoic lesion and a low attenuation lesion. Diagnostic was confirmed by spontaneous regression during following days. We shall encounter more frequently than nowadays this rare entity due to expanding tourism and P. falciparum resistance.

Adult↗
PubMedDate not supplied

[Advances in the medical treatment of bacterial endophthalmitis].

Currently, the systemic antibiotics intraocular penetration's rate is low and we have to perform intraocular antibiotics injections to reach levels above the minimal inhibitory concentration of the bacterial agents found commonly in endophthalmitis. Authors try to specify a rational strategy based on pharmacokinetics and bacteriological aspects of a new class of antibiotics, the fluoroquinolones, using their own studies and those from other teams about the intraocular distribution of these antibiotics. Further investigation is mandatory to assess the safety and efficacy of our first clinical results.

4-Quinolones↗
PubMedDate not supplied

[Infections and bone marrow autograft carried out for leukemias in children. Apropos of 47 cases].

This study included 44 children undergoing autologous marrow transplantation for leukemia between August 1979 and June 1987. Three of them received a second transplant. In the phase of neutropenia, 38 children presented with fever. Nineteen septicemia occurred (13 Gram positive cocci, 6 Gram negative bacteria), and 2 interstitial pneumonitis were observed. All children with documented infection or a fever of unknown origin recovered after treatment, except 3, who died from infection. The latest antimicrobial therapy used was a combination of an aminoglycoside and a third generation cephalosporin. When necessary, vancomycin or amphotericin B were added. After engraftment (granulocyte count greater than 0.5 X 10(9)/l) 14 septicemia (which recovered) and 10 herpes zoster infections were observed. Only one patient died of infection (herpes zoster with encephalitis).

Adolescent↗
PubMedDate not supplied

[Hematotoxicity of thiamphenicol. Report of two cases of acute erythroblastopenia (author's transl)].

Thiamphenicol is known to produce two hematological side effects: a decrease in blood cell count concerning mainly red blood cells; in this case regression is observed after withdrawal of the drug; the frequency of this side effect appears to be higher than that observed after chloramphenicol administration. Severe and sometimes fatal pancytopenia is rare and related to primary bone marrow failure; its incidence seems to be increased by high dosages, long-term or repeated administration, interaction with other hematotoxic drug administration, renal failure, elderly or immune suppression.

Acute Disease↗