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Biomedical subjects

J M Garat

Publications and source records attributed to J M Garat.

15 recordsLinked to original sources

Megautricles: embryogenic hypothesis.

We present 4 cases of megautricle emphasizing the relationship between it and the ejaculatory ducts. We develop an embryogenic hypothesis to explain the different forms of megautricles in relation to the seminal pathway.

Adolescent

Posterior urethroplasty with tubularized bladder mucosal graft.

Surgical management of long strictures of the posterior urethra is difficult and there is no concrete method that guarantees excellent results. The use of bladder mucosa has become established in the 1980s as treatment for anterior urethral reconstruction in hypospadias repair. We report 2 difficult cases (multioperations) of membranous urethral strictures treated with free tubularized bladder mucosal grafts with good initial results.

Adult

Thoracic ureter.

We report a case of a somewhat dilated ascending and descending ureteral segment penetrating into the thorax with moderate symptoms. The diagnosis was made by excretory urography. To our knowledge, our case represents the first such report in the literature.

Humans

Balanitis xerotica obliterans in children.

This report is based on 7 children with balanitis xerotica obliterans. Of these patients 5 had stenosis of the urethral meatus that required meatotomy and the postoperative results were good. The frequency of balanitis xerotica obliterans in children at our center, as well as the findings of other authors, suggests that possibly more cases would be diagnosed during infancy if all dried foreskin were examined systematically.

Adolescent

Testicular pseudolymphoma.

Pseudolymphomas are reactive processes which by their morphology can be confused with lymphomas. They have been described in non-lymphoid organs (gastrointestinal tract, lung, breast, etc.), although cases have also been reported in the spleen. In this article we present the case of a 3-year-old child in whom the location was in the testes. It is the 4th case reported in the literature and the first in a child. The main criteria for establishing such a diagnosis are the delimitation of the lesion, the presence of mature lymphocytes intermingled with other cells which are mainly plasma cells of polyclonal type and the formation of lymphoid follicles with active germinal centers. A differential diagnosis within the testicle should be made with the lymphoma (primary or secondary), the leukemic infiltration and the seminoma with marked stromal lymphoid reaction.

Child, Preschool

[Bladder hemangiomas].

Three further cases of bladder hemangioma are reported. Two were adults, with a previous history of hematuria, diagnosed by endoscopy and treated by external radiotherapy. The other case was an 8 year old child, diagnosed by radiologic, CT scan and endoscopic examinations and confirmed by histology, for whom an attitude of expectant prudence was adopted.

Adult

Open instillation of formalin for cyclophosphamide-induced hemorrhagic cystitis in a child.

A child with massive hematuria, produced by cyclophosphamide-induced cystitis, was treated with open bladder instillation of formalin. To prevent vesicoureteral reflux, we inserted two Fogarty catheters. Intraoperative retrograde cystography was made to confirm that there was no reflux, extravasation or passage of contrast per urethra. The postoperative result was good with cessation of hematuria.

Child, Preschool

[Perineal ectopic testis].

Three further cases of perineal ectopic testis are reported and the published literature reviewed. Etiopathogenicity is discussed and emphasis placed on the need for perineal exploration in all cases of absence of testes from the scrotum. The most effective route of approach for repair is an inguinal one allowing replacement of the testis into the corresponding hemiscrotum without difficulty. Because of the histopathologic features involved, prognosis is better than that of cryptorchidism.

Child

[Neurogenic bladder caused by spinal cord traction].

A neurogenic bladder was the presenting syndrome in three cases of spinal cord traction. Of the typical symptomatic triad: neuro-orthopedic, cutaneous and urologic, the latter was of primary importance. Symptoms in the first case were incomplete bladder retention with distention of upper urinary tract, right-sided vesicorenal reflux and renal insufficiency. Six months after excision of a sacral lipoma and freeing of the filum terminale, micturition had become normal without residue, and renal function normalized. Right-sided reflux was corrected by submucosal advancement surgery with good results. The clinical history was more suggestive in the second case. Although inaugural symptoms were mictional, there was foot paralysis and a retrosacral lipoma above an abnormal hairy tuft in the upper part of the gluteal cleft. Operation revealed the presence of a dermoid cyst and a lipoma. Their excision combined with section of the filum terminale allowing ascension of the medullary cone. Marked clinical and urodynamic improvement was obtained with normal micturition and disappearance of incontinence. An anti-reflux operation suppressed residual reflux with good urographic results. Marked improvement in mictional disorders was obtained also in the 3rd case after excision of a sacral extradural lipoma and section of the filum terminale, allowing objective ascension of the medullary cone by 4 cm. A very detailed analysis was conducted of similar cases reported in the literature, about 2% of neurogenic bladders in children being affected. The importance of early diagnosis is emphasized as well as the essential need to establish a precise diagnosis of the lipoma of cauda equina and of medullary fixation. Early neurosurgery is justified by the high frequency of improvement in cases treated in this way.

Adolescent

Urethro-balanitis xerotica obliterans.

A clinical report of 5 cases of balanitis xerotica obliterans (BXO) with urethral involvement is presented. Involvement of the urethra in the BXO is emphasized and the fact that this process is often unnoticed, is stressed. The clinical and histological characteristics of this disease are described in its different localizations. Investigations are suggested to diagnose urethral involvement and the suitable therapy is outlined.

Adult

[Urethroplasties with bladder mucosa in hypospadias].

Urethroplasty with free grafting of tubulized vesical mucosa is a method of great interest for the solution of complex hypospadias, especially in multioperated patients. We prefer its use when the penis is erect and there is no redundant dorsal prepuce. We present 13 cases with an evolution that allows us to be optimistic about this technique.

Adolescent