PubMed Health⌕ Search

Biomedical subjects

J M Guerit

Publications and source records attributed to J M Guerit.

29 records · Page 2Linked to original sources

Unexpected myogenic contaminants observed in the somatosensory evoked potentials recorded in one brain-dead patient.

Visual, brain-stem auditory and somatosensory evoked potentials (EPs) have been recorded in a 53-year-old woman who fulfilled all criteria of brain death. We observed the persistence of 48 msec latency somatosensory activities. Their muscular, and not neural, origin was, however, suggested by their disappearance after curarization. The practical consequences of this observation are two-fold. On the one hand, more precautions must be taken before reaching the conclusion that central neural activities can be obtained in coma dépassé patients. On the other, it suggests a possible test to enhance the sensitivity of EPs in diagnosing brain death.

Brain↗

Pudendal cortical somatosensory evoked potentials.

To determine normal reference latencies pudendal cortical somatosensory evoked potentials were evaluated in 20 healthy volunteers. The dorsal nerve of the penis or clitoris was stimulated electrically and the cortical response was recorded from the CZ-2 point (2 cm. behind the central vertex). Reproducible responses were obtained and reference values were established.

Adult↗

Applications of surface-recorded auditory evoked potentials for the early diagnosis of hearing loss in neonates and premature infants.

The recording of Auditory Evoked Potentials (AEPs) in adults provides a non-invasive means of assessing the auditory system at its peripheral and central levels. In neonates and premature babies, technical, methodological and physiological constraints prevent the clinician from simply extrapolating from the adult data. Those constraints are discussed. In the light of this discussion, some limits on the validity of AEP recording in very young patients are proposed.

Age Factors↗

Hemispheric differences in the voluntary inhibition of movement.

Twenty normal, twenty left-, and fifteen right-brain injured subjects, all right-handed, were assigned a sequence of voluntary inhibition of 23 movements. The inhibition lapse was recorded. Statistical analyses indicated a high performance in the normal and a deficient performance in left-brain injured subjects, no influence of the neurological symptoms on groups' achievement, a handicap in the subjects affected by a frontal lesion in the right brain, a hierarchical clustering of items varying according to the groups, and an organ-group interaction.

Brain Diseases↗

The influence of ototoxic drugs on brainstem auditory evoked potentials in man.

To examine the short- and long-term consequences of ototoxic drug administration, the brainstem auditory evoked potentials (BAEP) have been recorded in patients undergoing treatment with aminoglycosides antibiotics. It appears that the rapidity of the i.v. injection influences the short-term consequences of the drug administration. The long-term consequences may be reversible. Their reversibility could depend on the status of the ear before the first injection of ototoxic drug. In conclusion, BAEP may be useful as a means of atraumatic monitoring of the auditory function of patients treated with aminoglycosides antibiotics, the non-invasive character of this technique allowing it to be repeatedly used in both adult and young patients.

Acoustic Stimulation↗

Prognostic value of preoperative flash and pattern visual evoked potentials for diabetic retinopathy vitrectomy.

In view of the continuing controversy about the prognostic value of preoperative visual evoked potentials in diabetic vitrectomy, we retrospectively studied 31 eyes undergoing vitrectomy for diabetic retinopathy after recording pattern and/or flash visual evoked potential recording. Preoperative pattern visual evoked potentials were of no prognostic value in these eyes but a decrease in the amplitude of preoperative flash visual evoked potentials was significantly correlated with unchanged or worsened postoperative visual acuity when compared with preoperative visual acuity (P = 0.0156, Fisher's exact test). Therefore, while acknowledging that diabetic vitrectomy functional prognosis is actually multifactorial, we still recommend recording preoperative flash visual evoked potentials for diabetic patients in whom significant opacities of the intraocular media preclude correct examination of the ocular fundus, because a decrease in peak III amplitude may indicate a guarded vitrectomy functional prognosis.

Adult↗