Basal cell hyperplasia of the prostate.
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Aged↗
Biomedical subjects
J M Guileyardo
Publications and source records attributed to J M Guileyardo.
Prevalence of latent prostate carcinoma in two U.S. populations.
The prevalence of latent prostate carcinoma, the suspected precursor of invasive carcinoma, was studied in 500 autopsy specimens from New Orleans, Louisiana, and found to be similar in both whites and blacks. The tumors were subdivided into latent infiltrative type (LIT) and latent noninfiltrative type tumor was measured by photographic techniques. A good correlation between size and histology was found: The mean size of LIT tumors was significanty greater than that of LNT tumors. Age-versus-size plots revealed a subset of large LIT lesions in blacks that was not found among whites of the same ages. This subset may account for the excess of invasive carcinomas in blacks. These results suggest that many latent carcinomas lack promotional stimuli to become invasive.
Adult↗
Renovasculopathies of hypertension in Hispanic residents of Dallas, Texas.
BACKGROUND: Mean blood pressure levels (MBP) appear to rise with age slowly in the population of Mexico City and more swiftly in the U.S. in the black and white population, judging from published survey data. Some evidence suggests that MBP rises at intermediate rates in Hispanics in the U.S. METHOD: This question is explored here in two ways, by review of published survey data and by a novel approach that uses renal tissues obtained from forensic autopsies to estimate MBP. Past studies have revealed good agreement between the two methods of estimating MBP. RESULTS: Good agreement is again observed from the results of this study. Results from both methods agree that MBP is much lower at all ages in Mexican men and women than in blacks and whites in the U.S. Both methods also agree that Hispanics in the U.S. demonstrate an intermediate rise in MBP. A speculative first look at a small sample of U.S. Hispanics suggest that MBP rates of recent immigrants tend to resemble those of Mexico, while MBP levels of migrants of long-term residence resemble the native-born U.S. populations. CONCLUSIONS: The findings underscore the need for definitive testing to confirm if Mexicans who relocate to the U.S. may acquire an acceleration of the renovasculopathies, and of the lifelong progression toward hypertension that this implies.
Adolescent↗