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Biomedical subjects

J M Hyman

Publications and source records attributed to J M Hyman.

3 recordsLinked to original sources

Risk behavior-based model of the cubic growth of acquired immunodeficiency syndrome in the United States.

The cumulative number of cases of acquired immunodeficiency syndrome (AIDS) in the United States has grown as the cube of time rather than exponentially. We explain this by interactions involving partner choice and sexual frequency in a risk-behavior model with biased mixing. This leads to a saturation wave of infection moving from high- to low-risk groups. If this description is correct, then the decreasing growth rate of AIDS cases is not due to behavior changes; rather it is due to the intrinsic epidemiology of the disease.

Acquired Immunodeficiency Syndrome

The need for national HIV databases.

Researchers and public health officials involved in surveying and forecasting the course of the HIV epidemic require complete and unfiltered information from many sources. Governments should respond by establishing national HIV databases.

Acquired Immunodeficiency Syndrome

Nonlinear pattern selection in a mechanical model for morphogenesis.

We present a numerical study of the nonlinear mechanical model for morphogenesis proposed by Oster et al. (1983) with the aim of establishing the pattern forming capability of the model. We present a technique for mode selection based on linear analysis and show that, in many cases, it is a reliable predictor for nonlinear mode selection. In order to determine the set of model parameters that can generate a particular pattern we develop a technique based on nonlinear least square fitting to a dispersion relation. As an application we present a scenario for sequential pattern formation of dermal aggregations in chick embryos which leads to the hexagonal array of cell aggregations observed in feather germ formation in vivo.

Animals