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Biomedical subjects

J M Klafta

Publications and source records attributed to J M Klafta.

23 records · Page 2Linked to original sources

Current understanding of patients' attitudes toward and preparation for anesthesia: a review.

A number of issues relating to patient education in anesthesia have been addressed in this review and, based upon the available data, some questions can be answered clearly. It is apparent both that a large minority of the American, British, and Australian public is under the misconception that anesthesiologists are not physicians and that the role of the anesthesiologist, both in and out of the operating room, is not fully understood. Many surgical patients, particularly younger ones, have fears about the anesthetic that are distinct from their fears about the surgery, the most common of them relating to waking up prematurely or not at all. Traditional attire for anesthesiologists is preferred by patients but does not appear to significantly influence patient satisfaction. While there are numerous putative advantages to improving patient rapport, good communication as judged by the patient is associated with a lower incidence of malpractice litigation. Preoperative instruction has been demonstrated to have benefit with regard to patient anxiety, postoperative pain, and length of hospitalization. It is also clear that patients' coping behavior varies considerably and strongly influences the usefulness of providing detailed preoperative information. Preoperative teaching should therefore be tailored accordingly. An issue that is less clear concerns the optimal methods for educating patients and the general public. Preliminary evaluation of videotape instruction has yielded somewhat encouraging results, but whether the preoperative visit, supplemented by videotape or in-hospital, on-demand television programming, or computer networks, such as the World Wide Web or home television, are the most effective and practical means for this education remains to be seen. How best to identify in a cost-effective way patients who would most likely benefit from more information is an important question that remains relatively unaddressed. Advances in surgical diagnosis and treatment and critical care have depended upon the development of anesthesia as a specialty. Our ability to continue to develop may depend upon our success in educating the public, politicians, and other health care professionals about what we do. The evaluation of educational methods for disseminating information about anesthesia thus may be important in determining the very future of our specialty and the quality of surgical and pain therapy that patients will receive.

Anesthesia, General↗

Choice of anesthesia and intraoperative monitoring for lower extremity revascularization.

The prevalence of significant coronary artery disease re-enforces the importance of careful preoperative and intraoperative management in patients undergoing lower extremity revascularization. This article presents a practical approach toward the evaluation of anesthetic risk and the proper use of anesthetic agents and monitoring devices to minimize morbidity. The role of general and regional anesthetic agents is discussed, and complications of both techniques are presented.

Anesthesia↗

Neurological and psychiatric adverse effects of anaesthetics: epidemiology and treatment.

The practice of anaesthesia has changed considerably over the past 20 to 30 years owing largely to technological advances in patient monitoring and an expanded and improved pharmacological repertoire. While patient safety in anaesthesia has greatly improved, the risk of neurological and psychiatric adverse effects of anaesthetics remains and is the focus of continued investigation. For example, a great deal of attention has recently been directed at intraoperative awareness. This adverse event can be caused by delivering an inappropriate amount or type of anaesthetic. Another risk of anaesthesia involves drug-induced unpleasant subjective states in patients. Those drugs most frequently associated with these states include ketamine, droperidol and scopolamine. This risk can often be attenuated by careful adjustment of drug dose and the use of adjunctive agents such as benzodiazepines which may produce amnesia of the unpleasant subjective state. While it is well established that modern anaesthetic drugs cause acute impairment of cognition and psychomotor functioning, there is little evidence that these drugs have long term impairing effects. Finally, a particular kind of surgery, cardiac surgery requiring cardiopulmonary bypass, can be associated with adverse neurological and psychiatric sequelae which, while not directly related to anaesthesia, are of intense interest to anaesthesiologists.

Anesthetics↗

The contribution of valves to saphenous vein graft resistance.

Saphenous vein resistance influences graft flow rates and may affect graft patency in lower limb revascularization. To quantitate specifically the contribution of saphenous vein valves to this resistance, 10 human saphenous veins (mean length 68 cm, diameter 0.42 mm, and 5.2 valves per vein) were perfused with water under carefully controlled pressure gradients designed to simulate different peripheral resistances in the outflow bed. The Reynolds number was maintained at 350 to 600, within the physiologic range for in vivo grafts. Veins were perfused under both venous (10 mm Hg) and arterial (100 mm Hg) mean pressures to determine the effects of distension on the overall resistance of the conduit. The valves were bisected according to Leather's techniques and flow was measured in both directions, antegrade (simulating "reversed" grafts) and retrograde (simulating "in situ" grafts). Data (mean +/- standard error) were normalized to the baseline flow for each vein with intact valves and expressed as a percentage change. Data were analyzed by means of Student's t test (p less than 0.05). Baseline antegrade flow with intact valves averaged 71.0 +/- 3.0 ml/min at pressure gradients (delta P) of 10 mm Hg and 95.0 +/- 2.6 ml/min for delta P = 20 mm Hg. After valve incision, antegrade flow (reversed) increased an average of 29% at both pressure gradients. Retrograde flow (in situ) through the bisected valves was only 19% greater than baseline antegrade flow and was significantly less than antegrade flow through bisected valves. The difference is explained by theoretic considerations of stenosis area and orifice shape. The increases in flow did not correlate with vein length or diameter, nor did flow change with different distension pressures.(ABSTRACT TRUNCATED AT 250 WORDS)

Blood Vessel Prosthesis↗