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Biomedical subjects

J M López Chozas

Publications and source records attributed to J M López Chozas.

4 recordsLinked to original sources

[Behavior of the night decrease of arterial pressure after suppression controlled of the antihypertensive medication].

OBJECTIVE: The patients with hypertension who do not present a night decrease of the arterial pressure are a bigger degree of target organ damage due to the supported hypertension. In our work we analyzed after ambulatory blood pressure monitoring (ABPM) the prevalence of the condition dipper of the patients with hypertension of degree 1 and/or 2 after the suppression controlled of the antihypertensive medication; as well as the magnitude of the effect of white coat (object of another study). DESIGN: Almost experimental study and descriptive. SETTING: Primary care. Urban health centre. Participants measurements and results. Studies of ABPM were realized in 70 essential hypertense patients with good control of the arterial pressure after pharmacological treatment before suspending the antihypertensive medication (1 phase) and to the 4 weeks of leaving the treatment (2 phase), two periods being programmed: diurnal and night. RESULTS: Of all 70 hypertense patients, 18 (26%) did not manage to carry out 2 ABPM since after the retreat of the medication there presented blood pressure unacceptable values that forced to re-introduce the medicaments. The 79% of the hypertense patients were dipper after the 1 monitoring and that after the suppression of the antihypertensive medication, 83% was continuing being dipper. Depending on the gender there were no statistically significant differences as for the night decrease of the arterial pressure in both periods. Finally, 75% and 11.5% of the patients were dippers or not dippers, respectively, in both phases and only 13.5% of the patients it changed its condition. CONCLUSIONS: The retreat of the medication in hypertense of degree 1 and/or 2 well controlled does not modify the patients' percentage with night decreases of the blood pressure.

Adult↗

[Subacute thyroiditis associated with positive antibodies to the Epstein-Barr virus].

Subacute thyroiditis is an inflammatory disorder of the thyroid caused probably by viruses. It is clinically characterized by the presence of anterior cervical pain and/or painful goiter, and rarely as fever of unknown origin or as prolonged fever syndrome. We report a case of a 49-year-old female admitted to the hospital because of fever during last month, leukocytosis and accelerated erythrocyte sedimentation rate. Following observation, slight tenderness over the thyroid gland and signs of hyperthyroidism occurred. After the laboratory studies, low thyroidal radioactive iodine uptake and fine-needle aspiration cytology (FNAC) of thyroid, she was diagnosed of subacute thyroiditis with hyperthyroidism. We believe that the etiologic agent was the Epstein-Barr virus because heterophile and Epstein-Barr virus-specific antibodies were positive. The patient was treated with acetaminophen (1.500 mg/day) with prompt and complete resolution of the clinical and laboratory abnormalities. There has been no recurrence of the disease during a 1 year follow-up.

Antibodies, Viral↗