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Biomedical subjects

J M Last

Publications and source records attributed to J M Last.

At least 19 recordsLinked to original sources

Obligations and responsibilities of epidemiologists to research subjects.

Some important obligations and responsibilities of epidemiologists to research subjects include protecting the welfare of research subjects; proper conduct relating to informed consent; protecting privacy and maintaining confidentiality; communicating pertinent aspects of the research to study subjects; respect for the cultural setting in which the research is conducted; informing the study population about risk factors that the investigation discloses; and ensuring that economic or political consequences of the research findings do not harm the study subjects. These are discussed in this paper in the context of basic principles of biomedical ethics.

Communication

Homo sapiens--a suicidal species?

Preparations should be made now to counter the expected effects of environmental damage on health. Otherwise humanity may have to pay a very high price for plundering the world's resources.

Climate

Making the most of research.

The results of research are worthless if they are not used. Efficient two-way communication between the producers and users of scientific studies helps to prevent this from happening.

Communication

Distinguishing child diagnostic types with early memories.

The present study attempts to correct design weaknesses in earlier studies which assessed the use of early memories (EMs) in identifying psychopathology in children. A new EM scoring system, the CEMSS, was developed to provide an objective, comprehensive analysis of the reported EMs. Subjects were 64 boys, SES IV and V, 8 through 12 years old from four diagnostic groups--Delinquent, Hyperactive, Somatic Complaints, and Schizoid. Overall, the CEMSS provided an effective means to distinguish the diagnostic groups, p less than or equal to .01. The results suggest that content variables best distinguished the type of presenting psychopathology, whereas an earlier study found that structural EM variables most reliably identified the degree of psychopathology.

Attention Deficit Disorder with Hyperactivity

Biomass fuel combustion and health.

Biomass fuels (wood, agricultural waste, and dung) are used by about half the world's population as a major, often the only, source of domestic energy for cooking and heating. The smoke emissions from these fuels are an important source of indoor air pollution, especially in rural communities in developing countries. These emissions contain important pollutants that adversely affect health-such as suspended particulate matter and polycyclic organic matter which includes a number of known carcinogens, such as benzo[a]pyrene, as well as gaseous pollutants like carbon monoxide and formaldehyde.Exposure to large amounts of smoke may present a health risk that is of a similar order of magnitude to the risk from tobacco smoke. The effects on health arising from exposure to air pollution are reviewed, based on what has been reported in the literature so far. Further and more detailed information on exposures and on the epidemiological aspects is urgently required.The persons most frequently affected are women who do the cooking for households in rural villages; they suffer from impaired health due to prolonged and repeated contact with these harmful pollutants. When they are pregnant, the developing fetus may also be exposed and this leads to the risk of excess deaths. In the developing countries, exposure to biomass fuel emissions is probably one of the most important occupational health hazards for women. A conservatively estimated 300-400 million people worldwide, mostly in the rural areas of developing countries, are affected by these problems.

Air Pollutants

Management of primary bladder cancer by a multidisciplinary team.

Results of management of a closed series of primary bladder carcinoma over a 20-year period by a multidisciplinary team are presented. Patients were classified by the TNM method before treatment. These experiences indicate that stage and grade are relevant to prognosis and treatment. The TNM classification can be precise and practical when used diligently by a treatment team. Although no new methods of treatment are offered, the treatment now available may be utilized to better effect if programmed to allow care of the patients by a team, especially if the team explores the limits of radiation and surgery in their hands.

Adenocarcinoma