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J M Layton

Publications and source records attributed to J M Layton.

8 recordsLinked to original sources
PubMed1990

A validity study of four empathy instruments.

The construct validity of four empathy instruments were evaluated through examining group differences and correlations between tests. Subjects were 18 registered nurses (RNs) and 32 nursing assistants (NAs). Instruments used were the Empathy Test (Layton, 1979), the Carkhuff (1969a, 1969b) Empathic Understanding in Interpersonal Processes Scale, the empathy subtest of the Barrett-Lennard (1962) Relationship Inventory, and LaMonica's (1981) Empathy Construct Rating Scale (ECRS). The first hypothesis, that RNs would score significantly higher than NAs on all empathy measures, was confirmed (p less than .0003 to p less than .027). The second hypothesis, that the various empathy measures would be positively related, was partially confirmed. The Carkhuff scale was significantly correlated with the ECRS (r = .25, p less than .05). The ECRS and the Barrett-Lennard also were correlated (r = .78, p less than .001). Results are interpreted using Barrett-Lennard's (1981) theory of empathy.

Data Collection↗
PubMed1988

A comprehensive immunotopographic map of human thymus.

We have achieved a comprehensive immunotopographic mapping of human thymus by using a large battery of monoclonal antibodies and the methodological refinement of comparative serial tissue section immunohistochemistry, allowing analysis of multiple phenotypes in the same tissue site. Previous immunohistochemical studies of thymus have concentrated on the majority T-cell and epithelial cell populations. Besides demonstrating the complexity of T-cell antigenic expression (e.g., simultaneous cortical expression of Leu 2, Leu 3, CALLA, Tdt, and Leu 6), we delineate surprisingly complex B-cell zones (e.g., septal B-follicles with DRC+C3d+ dendritic cells and zonal maturation of B-cells). Whereas septal B-follicles were found in 25% of cases, medullary B-cells were universally present as a substantial minority component. This expanded immunotopographic knowledge of the complex T-, B-, epithelial, and reticulum cell neighborhoods suggests that the thymus is an organ capable of a broad repertoire of immunological responses, not limited to T-cell development.

Adolescent↗
PubMed1979

Sensitivity of mammography and physical examination of the breast for detecting breast cancer.

Mammography and physical examination of the breast are evaluated as screening instruments for detecting breast cancer based on local biopsy data obtained from women enrolled in a national breast cancer screening program. One hundren thirteen cancers (15.5%) of women who underwent biopsy) were detected. The individual sensitivities of mammography and physical examination for detecting breast cancer are 62% and 24%, respectively. The sensitivity of the two methods combined is 75% (85 of 113). Thirty-seven cancers were in situ or minimally invasive (less than or equal to 1 cm in greatest dimension). Eighty-one percent (30 of 37) of these small cancers were detected by screening, and they comprised 35% (30 of 85) of all cancers detected by mammography, physical examination, or both. Improved survival is anticipated due to this high rate of discovery of small cancers.

Adult↗