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J M Lopez Pila

Publications and source records attributed to J M Lopez Pila.

9 recordsLinked to original sources
PubMed1989

Lack of evidence for strand-specific inhibition of poliovirus RNA synthesis by 3-methylquercetin.

Buffalo Green Monkey cells were infected with poliovirus-1 in the presence of 3-methylquercetin or guanidine, and the formation of positive- and negative-strand viral RNA was monitored using single-stranded RNA probes. Both 3-methylquercetin and guanidine prevented the formation of plus-strand as well as minus-strand viral RNA, although, due to the high multiplicity of infection used, a high number of genomic viral RNA was always present in the cells.

Animals↗
PubMed1988

[Adsorption of selected enteroviruses on sand from a groundwater stratum: effect of pH, grain size, water solutes and organic contamination].

Elimination of human pathogenic viruses during the filtration of contaminated water or during groundwater recharge with surface water relies a great deal on the adsorption and permanent binding of the viruses to the soil or to the aquifer material. In the present study we have investigated the influence of organic contamination, of grain size, and of the presence of several ions and other compounds on the adsorption of four enteroviruses to sand. Results showed an impaired adsorption of viruses in organic contaminated soil. Smaller sand grain sizes, specially the colloidally suspended particles, did bind viruses more efficiently than the larger ones. This points to the possibility of designing filters containing sand of reduced grain sizes where elimination of viruses is a main objective. Several cations increased the binding of viruses to sand and caused the viruses to aggregate. This property might be taken advantage of during coagulation-sedimentation processes, in order to optimize viral reduction.

Adsorption↗
PubMed1986

[The ATP concentration of drinking water compared to the colony count].

During a four months' period we have monitored the drinking water of the city of Berlin for its ATP-content and for its Total Colony Count. After concentrating the drinking water by a factor of 1000 by filtration, we obtained ATP-values which were always significantly above the blanks. The profile of the ATP-values roughly paralleled that of the Colony Counts; however, as we never observed Colony Counts nearly approaching 100 colonies/ml (which is the value not to be exceeded according to current German Law), we are unable to positively assess how the ATP-value would have behaved in samples with Colony Counts above 100 ml. Analysis of increasing dilutions of sewage tested for both Colony Counts and ATP indicate that values above 100 colonies/ml would have yielded ATP-values well above those normally seen in drinking water. Therefore, ATP could probably be taken as a measure for the Total Colony Count.

Adenosine Triphosphate↗