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Biomedical subjects

J M Morán Penco

Publications and source records attributed to J M Morán Penco.

At least 19 recordsLinked to original sources
PubMed2005

[Acute secundary abdomen to pancreatic hydatid cyst].

The hydatidosis is a frequent zoonosis in Spain, but isolated location in pancreas and their onset as acute abdomen is excepcional. We present a boy 14 years old, with abdominal pain and low-grade fever since 1 month. Hemogram shows eosinophilia, and echography an anechoic mass in tail of pancreas beside of free peritoneal liquid. At surgery procedure: a broken hydatid cyst is verified, surrounded of tissues inflammatory reaction that evolved to pancreatic fistula. The differents forms from clinical presentation of the pancreatic hydatid cyst, as well as the complications related to their location are analyzed.

Abdomen, Acute↗
PubMed2003

[Photopheresis: new immunomodulatory therapy for T-lymphocite mediated diseases].

The photopheresis (ECP) is a therapeutic approach based on the biological effect of psoralen and ultraviolet light A on mononuclear cells collected by apheresis, and reinfused into the patient. In 1988, the treatment was the first FDA-approved selective immunotherapy for any type of cancer. Convincing data taken from over 160 centers in Europe and the U.S.A. over the past few years have documented that ECP is associated with a very low side-effect profile. Evidence shows that this therapy prolongs the mean survival, and also induces 50-75% response rates in patients with advanced cutaneous T-cell lymphoma. In addition, more and more reports indicate that photopheresis is a potent agent in the therapy of solid organ transplant rejection, graft versus host disease, scleroderma, and other autoimmune diseases resistant to conventional therapy. The mechanism of this treatment is likely due to the induction of cell-mediated anticlonotypic immune response against pathogenic clones of T lymphocytes.

Adjuvants, Immunologic↗
PubMed2003

[Epidermoid cyst of the mouth floor].

The epidermoid cysts are frequent during childhood, however mouth floor location are very unusual, because of their more difficult diagnosis and therapeutic approach. We present a 5 years old male, symptoms free until a week before, when his parents noticed a well defined mass in the mouth floor. A physical examination leaded to the diagnosis of possible epidermoid cyst. The tumor was excised through an introral approach. A review of different diagnostic means and surgical management are undertaken.

Child, Preschool↗
PubMed2001

[Retroperitoneal cystic lymphangioma in childhood].

UNLABELLED: Lymphangiomas are very common neoplasms in infancy. However, a retroperitoneal location is seldom observed. We present the case of a male with a history of chronic recurrent pain over a period of several years. An X-ray showed a calcic density in the left upper abdominal quadrant; the histological study revealed it to be a mixoid cystic lymphangioma. Clinical presentation varies greatly from an asymptomatic mass to serious complications. In order to correctly diagnose of these neoplasms it is essential to carry on ultra sound and CT examination although a simple abdominal X-ray may show calcifications as the one presented here. Treatment is always surgical and a complete extirpation should be performed, unless vital structures were are involved. Treatment with laser, fibrin and sclerotherapy have also been used. CONCLUSION: In spite of being benign neoplasms we believe they should be removed to confirm diagnosis and avoid possible complications.

Child↗
PubMed2001

[Hydatic cyst in mediastinum].

The main localization of hydatic cysts (HC) in mediastinum is exceptional. We present the case of a 12 year-old boy who had habitual contact with dogs. He had pain in the right hemithorax and back together with low-grade fever. In the X-rays of the thorax a right retrocardiac image shows an occupied costodiaphragmatic sinus. The CT of the thorax shows a bilateral pleural effusion and a mass measuring 10 x 7.5 x 5 cm in the middle mediastinum. After admission, a new X-ray of the thorax revealed an increase in the right pleural discharge, for which reason an urgent thoracotomy was performed checking for the existence of a mediastinum HC with possible membrane fissures. The HC was removed. The only treatment of HC in mediastinum is surgical, an urgent thoracotomy being necessary whenever a possible rupture is suspected in order to avoid a possible anaphylatic reaction or growth pleural cavity.

Child↗
PubMed1999

[Hemangioma of the glans penis].

The haemangiomas are benign vascular tumors of frequent apparition in infant, but not very much described in penis glans in the literature. We present a case with location in penis glans, in a short age male, that it was treated through conventional surgery with good results. We accomplish a review of this pathology and we make reference to the different ways of treatment today.

Child↗
PubMed1998

[Superior vesical fissure].

Although vesical extrophy is a well-known anomaly, the variants of vesical extrophy are exceptional. We present the case of a newborn child, who upon exploration, revealed a defect of closure in the infra-umbilical abdominal wall through which vesical mucous membrane protruded. A probe introduced into the urethra appeared externally at the place of the infraumbilical defect. Following the diagnosis of superior vesical fissure, resection of the protruding vesical mucous membrane and closure were carried out. The authors reviewed the bibliography published in order to study the different kinds of variants of vesical extrophy and the associated congenital anomalies. Although these children are usually continent, a urodynamic study and a VCU are recommended in order to discard the existence of a post closure-uretheral-vesical reflux of the umbilical defect.

Female↗
PubMed1994

[Abdomino-scrotal hydrocele, an unusual disease, review of the literature, and report of a new case].

Abdominal-scrotal hydrocele is an uncommon lesion, most specially during childhood. It is an entity, though, that should be included in the differential diagnosis of abdominal masses in children, and also considered as a likely cause of ureterohydronephrosis. Diagnosis is arrived at through ultrasound, CAT and occasional excretory urography. Radical surgical excision using inguinal access is the recommended approach, but sometimes the inguinoabdominal or pure abdominal approaches can be performed. Following surgical ablation the cure is complete, and includes remission of the ureterohydronephrosis when present. This paper reviews the literature, presents one case and discusses both the diagnostic possibilities and therapeutic alternatives.

Abdomen↗
PubMed1990

[Interferences between nutrients in their absorption from the peritoneal cavity in rats].

With the aim of detecting possible interferences in the absorption of glucose, amino acids and fats we infused several combination of them into the peritoneal cavity of the Wistar rats. After intraperitoneal infusion of 2 mu Ci-L-glucose-C14 with 5 ml of D-glucose 5 per 100 and L-glucose-C14 with 5 ml of "16N" 3.5 per 100 in different groups of animals, we detected slight differences in plasma radioactivity one hour after infusion. We also found moderated differences in plasma radioactivity among the groups of animals infused with 1 mu Ci of fat radioactive amino acids plus 5 ml of D-glucose 5 per 100 and in the group infused with 1 mu Ci of 5-L-amino acid-C14 plus 5 ml of "16N" 3.5 per 100, after four hours of the infusion. We found no differences among those groups of animals infused with fat plus glucose and with fat plus amino acid with respect to those infused with fat alone. In summary, as glucose and amino acid absorption pathway are the same (capillary flow) seem reasonable that they interfere with each other when they are infused intraperitoneally. Fat infusion that not seem to interfere with other substrates possible due to the different absorption pathway (lymphatic channels) but further studies are needed to determine this.

Absorption↗
PubMed1990

[Axial computed tomography in anorectal malformations: a pre- and postoperative indication?].

Ten patients with anorectal malformations were studied by preoperative CT: well developed sphincteric muscular structures (puborectal sling of levator ani, muscular striated complex and external sphincter) were present in six patients. In three patients muscular structures were poorly developed (case 2a with rectovaginal fistula, case 5a with rectocloacal fistula and case 7a with prostatic fistula). In one case with bladder fistula, the sphincteric musculature was not identified at all. Eleven patients were postoperative studied by pelvic CT: Two of 11 cases had a good sphincteric control. The other nine patients were incontinent. In three of the nine incontinent patients, the colon was appropriately place, but puborectal muscle and sphincteric complex were hypoplastic. In the other six cases CT showed a pulled through colon out of the sphincteric structures. Four of them presented major bony sacral abnormalities and/or lesion of the sphincteric muscle structures. The remaining two patients with an evident pulled-through colon out of a normally developed sphincteric region and without sacral anomalies, were selected for a secondary PSARP procedure. In one of these two patients the operation brought about a complete resolution of the fecal incontinence. The pelvic CT is a useful examination in the anorectal malformation for the preoperative prognostic evaluation of continence, while postoperative CT is essential in selecting those incontinent patients who need a secondary PSARP for the treatment of fecal incontinence.

Anal Canal↗
PubMed1988

[Hirschsprung disease: histochemical technic for alpha-naphthyl-esterase in the intraoperative diagnosis of the proximal extent of the aganglionosis].

Intraoperative biopsies are required to confirm diagnosis of Hirschsprung's disease and to determine exact extent of aganglionism. Authors report a new method for enzymo-histochemical intraoperative evaluation of aganglionic segment. Activity of non specific esterase (following Davis and Orstein technique, 1959) has been used to demonstrate presence or absence of intramural ganglion cells in sero-muscular intestinal biopsies, which had been taken at various levels in 34 patients with preoperative diagnosis of Hirschsprung's disease. Authors consider histochemical technique as the most reliable, quick, simple and low-cost method for intraoperative evaluation of the length of aganglionic segment and, of course, to confirm diagnosis. Alpha-naphthyl-esterase is also of great help in the study of so-called pseudo-Hirschsprung.

Biopsy↗
PubMed1984

[Treatment with Soave's technic and long-term results in 270 cases of Hirschsprung disease].

The authors present the surgical technique for the correction of Hirschsprung disease following SOAVE's original description. A series of 270 cases observed in 20 years at the Pediatric Surgery Department of the "Instituto Giannina Gaslini" in Genova, Italy, are examined. These cases, all treated by surgery, were followed up in long term for more than one year both clinically and radiologically. Additionally 73 cases treated from 1977 on were also followed up with the aid of ano-rectal electro-manometry. The most recent diagnostic aspects are discussed, such as ano-manometry, and some conclusions are drawn about long term results.

Anal Canal↗
PubMed1983

[Omental graft, without devascularization, in the hepatic hilum. Experimental study].

Epiploon grafts were made into the resected hepatic hilum of dogs with the aim of creating anastomosis between the intrahepatic and epiploic lymphatic systems. Various hepatic enzymes were observed over a three month period, and then a histopathological study of the grafted area was made. This type of graft was also applied to rabbits, after tying off the common hepatic duct, and the histopathological study made fifteen days after. The results show no lymphatic anastomosis between the liver and the grafted epiploon. So we would not advise using this type of technique to drain intrahepatic cholestasis in biliary atresia, at least not as the procedure of choice.

Animals↗