Biomedical subjects

J M Moses

Publications and source records attributed to J M Moses.

At least 19 recordsLinked to original sources

PubMed1991

Adverse events following measles-mumps-rubella and measles vaccinations in college students.

We studied adverse events reported by 401 measles, mumps and rubella (MMR) vaccinees and 391 unvaccinated controls at one college, and 133 measles (M) vaccinees and 352 unvaccinated controls at an adjacent college during a measles outbreak in Massachusetts in 1985. Rates of symptoms and signs experienced by MMR vaccinees, M vaccinees, and controls were essentially similar. No serious adverse events were detected.

Adolescent↗

PubMed1979

Pleuropericardial reaction to treatment with dantrolene.

Chronic pleural effusion occurred in three patients, one of whom also developed acute pericarditis. A fourth patient developed both pleural and pericardial effusions. All patients had been receiving dantrolene sodium for at least two months. The pleural fluid was a sterile exudate with pleural and peripheral blood eosinophilia in all patients. No pulmonary parenchymal involvement was apparent. Pleural biopsy specimens showed nonspecific inflammation. Resolution of the pleural process was prolonged after dantrolene therapy was discontinued. Although a causal relationship between dantrolene and serosal inflammation remains unproved, this association in four patients warrants careful observation of others receiving long-term dantrolene therapy.

Acute Disease↗

PubMed1979

Annular constricting bands.

We reviewed forty-five patients with congenital constriction bands with an average follow-up of 15.8 years. The family history and associated anomalies were recorded and particular attention was paid to temperature gradients and neurocirculatory deficits with respect to band location. No family history of band constrictions was elicited. Most of our patients were products of first pregnancies and of young mothers. Deformity of the nails was a constant finding in patients with distally located bands. All patients demonstrated at least one other anomaly, most commonly a malformation of the hand. Neural deficits were noted in 23 per cent of the patients, while circulatory findings appeared in 16 per cent. A significant temperature gradient averaging 2.38 degrees Celsius was noted in twenty patients in whom the bands were located proximally. All patients with neural deficits demonstrated a significant temperature gradient. Staged z-plasty was the procedure of choice in surgical release of constriction bands.

Abnormalities, Multiple↗

PubMed1976

Nonfatal cervical spine injuries in interscholastic football.

The incidence of nonfatal neck injuries in high school football was determined by performing preseason examinations in 104 active high school players and 75 college freshman candidates. Coaches of all 430 Iowa high schools were asked to recall the number of players experiencing significant neck pain during the season. A detailed questionnaire for each injury was also completed by a sample population of 60 coaches. The incidence of roentgenographic evidence of neck injuries was as high as 32% and was related to years of experience. Injury was most likely to occur to a linebacker or a defensive halfback when they tackled the ball carrier. In the preseason examination, half the players who volunteered a history of significant neck pain had abnormal x-ray films.

Adolescent↗

PubMed1975

Dynamics of nap sleep during a 40 hour period.

Following 1 baseline night, the sleep of 8 adult males in equally space 1 h naps during a 40 h period was examined. Ten additional subjects were sleep-deprived for 40 h with 1 h periods of exercise given in place of naps. One recovery night followed the 40 h period for both groups. Total sleep time and the amount of stage REM during the naps were negatively related to the circadian-temperature cycle. Stage REM frequently appeared within 10 min of stage 1 onset and the normal sequence of stages REM and 4 were altered, demonstrating that the organization of sleep within a nap is quite different from that in monophasic nocturnal sleep. Auto-correlation and cross-correlation analyses showed that the relation of sleep stages from hour to hour in normal continuous baseline sleep was altered in nap-to-nap comparison. The timing of REM onset may be controlled by a sleep-dependent ultradian clock; the clock may stop upon awakening and resume at the next sleep onset. Naps had recuperative value in terms of maintaining the normal amounts of sleep stages on the recovery night; recovery sleep for the exercise group showed typical sleep-loss effects.

Adult↗

PubMed1975