PubMed Health⌕ Search

Biomedical subjects

J M Neale

Publications and source records attributed to J M Neale.

18 recordsLinked to original sources
PubMed1992

Medication status of participants in psychopathology research: selective review of current reporting practices.

The majority of Ss included in studies of psychopathology are typically receiving psychoactive medication. In view of concerns regarding the confounding effects of psychoactive medication, it appears that researchers should provide information regarding at least the drug status of the Ss studied. A review of the articles on adult psychopathology that appeared in the Journal of Abnormal Psychology during a 5-year period, however, revealed that nearly 50% of reports on Ss presumably receiving psychoactive medications failed to specify the medication status of those Ss. Few studies (15%) provided adequate information regarding the types and dosages of psychoactive drugs received by the Ss. It is argued that researchers should provide a full report of the psychoactive drugs received by research participants and, when participants are unmedicated, to indicate the reasons for drug-free status.

Bias↗
PubMed1992

Development of common cold symptoms following experimental rhinovirus infection is related to prior stressful life events.

Previous studies of rhinovirus infection indicate that about one third of the persons with confirmed viral infection do not show evidence of cold symptoms. Factors that determine which infected individuals will develop colds are not known. Using a rhinovirus inoculation protocol, the authors explored the possible role of recent life events, current mood, and perceived stress in the development of symptoms in individuals known to be infected. As part of a larger study, 17 subjects were exposed to a rhinovirus and were individually isolated for 5 consecutive days; cold symptoms, mucus weights, and tissue use were monitored on a daily basis during this period. Although all 17 subjects had confirmed rhinovirus infection, only 12 subjects developed clinical colds, as indicated by self-reported symptoms and by objective symptom indices. The average number of reported major life events for the previous year was significantly higher for those who developed colds than for those who did not (p < .05). Measures of affect and perceived stress before the inoculation were not different for those who did and did not develop colds. Complementing recent research demonstrating psychosocial influences on experimental infection rates, these results provide evidence that the development of cold symptomatology in experimentally infected individuals is related to prior life events.

Adolescent↗
PubMed1991

An alternative statistical treatment for summarizing the central tendency of replicate assay data.

Standard assay procedures call for multiple replicates for the purpose of averaging random error from individual replicate scores to obtain a reliable estimate of the true score and for the purpose of specifying the degree of variability within the assay. In this paper we focus on the variability and magnitude of within-assay replicates in order to improve the estimate of the true score. A rule is presented for deciding (1) when individual replicates should be omitted from the computation of the assay's summary score or (2) when an entire sample of replicates should be discarded based on the pattern of replicate scores. It is suggested that this rule improves the reliability of the estimated assay score and this is supported by an illustrative analysis of lymphocyte proliferation assays.

Data Interpretation, Statistical↗
PubMed1990

Self-focused attention, coping responses, and distressed mood in everyday life.

Several questions concerning the relation between self-focused attention and depressed mood were examined: (a) Does the association involve global negative affect, rather than sadness per se? (b) is self-focus associated with specific negative affects other than sadness? and (c) does the association occur at the between-subjects or within-subject level? Also hypothesized was that self-focus is associated with coping responses that may perpetuate negative mood. In an idiographic/nomothetic design, 40 male community residents completed daily reports for 30 days. Results suggest that self-focus is linked with global negative mood as well as specific negative affects other than sadness and that the association occurs on a between-persons, rather than a day-to-day within-person, basis. In addition, highly self-focused men reported using passive and ruminative coping styles, which in turn were associated with distressed affect.

Adaptation, Psychological↗
PubMed1990

Effects of caring for a demented relative on elders' life events and appraisals.

Weekly ratings of events and appraisals were collected from 19 caregivers of dementia patients and 19 control subjects over 4 weeks. Caregivers reported more negative events overall and rated them as more undesirable than did control subjects, but significant differences were found in events of only 2 of the 11 life areas that were measured. Caregivers' negative appraisals were more frequent and more intense than those of control subjects in virtually every life area. These preliminary data fail to demonstrate a global disruption of caregiver's activities and suggest the importance of appraisals in determining the impact of caregiving.

Aged↗
PubMed1978

Cognitive slippage in children vulnerable to schizophrenia.

Psychological deficit research with adult schizophrenics has been hindered by numerous methodological problems that may be avoided by the prospective study of children vulnerable to the disorder. An object sorting task was administered to 156 children of schizophrenic patients, 102 children of depressed patients, and 139 children of normal parents. The children were between 6 and 15 years old. The children of schizophrenic parents made fewer "superordinate" sorting responses than those of normal parents, and more "complex" sorts (a category of inadequate responses) than children of either normal and depressed parents. Our analyses showed that these deficits could not be explained by differences in intelligence. These deficits in conceptual performance may reflect the genotypic predisposition to schizophrenic and/or represent an early precursor of later maladjustment.

Adolescent↗
PubMed1978

Peer evaluations of the competence of children vulnerable to psychopathology.

Peer evaluations of the behavior of 75 children of schizophrenic mothers, 57 children of depressed mothers, and 153 controls were collected using the Pupil Evaluation Inventory. The children, both boys and girls, were in grades 2 through 9. Both male and female children of schizophrenics were viewed more deviantly than controls on Aggression and Unhappiness-Withdrawal factors. Only the female children of schizophrenics were viewed as less likable than controls. In general, children of schizophrenics did not differ from children of depressives. The exception was the older daughters of schizophrenics, who were rated as more deviant than members of both the remaining groups.

Adolescent↗
PubMed1978

ASSESS: Adjustment Scales for Sociometric Evaluation of Secondary-School Students.

The Adjustment Scales for Sociometric Evaluation of Secondary-School Students (ASSESS) was designed to assess peer ratings of the behavior of male and female adolescents. Five scales were developed and cross-validated: Aggression-Disruptiveness, Withdrawal, Anxiety, Social Competence, and Academic Difficulty. Evidence of adequate internal consistency and test-retest reliability was presented. Evaluations by male and female classmates were highly correlated. Sex and age differences accounted for only a small proportion of the total variance.

Achievement↗
PubMed1976

The Pupil Evaluation Inventory. A sociometric technique for assessing children's social behavior.

The Pupil Evaluation Inventory was developed to assess peer ratings of the behavior of male and female children in grades one through nine. Three homogeneous and stable factors emerged from a factor analyss: Aggression, Withdrawal and Likeability. High interrater agreement between male and female raters, stability of factorial structure, high internal consistency, and moderate concurrent validity were found across sex and grade levels. Test-retest reliability was high for a separate sample of third and sixth graders. There was a tendency for higher internal consistency and teacher-peer correlations for the Aggression factor.

Adolescent↗
PubMed1975

Children vulnerable to psychopathology: the Stony Brook high-risk project.

The study of children at risk for the development of schizophrenia is a promising research strategy for increasing our understanding of the etiology of schizophrenia. This paper describes the methods and procedures of such an investigation. Three groups of children are being followed: those who have a schizophrenic parent, those who have a depressive parent, and tose whose parents have no psychiatric history. There are three major foci of our assessment procedures. First, the patient, spouse, and family environment are examined. Second, the children are assessed in school from the vantage point of both peers and teachers. Finally, the children are tested with several laboratory measures of cognitive processes, attention, emotional responsivity, and social interaction.

Achievement↗
PubMed1975

Teacher ratings of children vulnerable to psychopathology.

Teacher behavior ratings were collected on children of schizophrenic, depressed, and normal mothers. Children of schizophrenic and depressed mothers were rated higher than were children of normal mothers on classroom disturbance, impatience, disrespect-defiance, and inattentiveness-withdrawal; they were rated lower on comprehension, creative initiative, and relatedness to teacher.

Adolescent↗
PubMed1975

Abstract conceptualization in schizophrenia: a fundamental psychological deficit?

Wright (1975) has recently argued that impairment in abstract conceptualization is an important schizophrenic deficit. We contend that the data to which he refers are insufficient support for that conclusion. Although schizophrenics' performance on sorting tasks may be less efficient than that of some other groups, the significance of this finding is debatable. A differential deficit in conceptual ability has not been shown and the confounding effects of third variables have not been ruled out. In addition, the validity of sorting techniques in measuring abstraction has not been adequately established. These methodological issues have a more general applicability to the study of psychopathology. Appreciation of them and a more specific definition of "acceptable evidence" would reduce considerably the continuing state of confusion in research on psychological deficit.

Association↗