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Biomedical subjects

J M Oxbury

Publications and source records attributed to J M Oxbury.

5 recordsLinked to original sources
PubMed1976

Recovery from unilateral visuo-spatial neglect?

Patients who had demonstrated unilateral visuo-spatial neglect on a simple drawing and copying task three to four weeks after a right hemisphere stroke were reassessed five months later. Although the incidence of neglect as defined had dropped markedly in that period, they remained impaired on tests of spatial analysis and visual perception relative to a group of right hemisphere patients without neglect. The measurement of neglect is discussed in the light of both these results and the stability of the neglect group's abnormal position preference on one of the tests administered.

Cerebrovascular Disorders↗
PubMed1976

A blind controlled trial of dextran 40 in the treatment of ischaemic stroke.

A blind controlled trial of dextran 40 in ischaemic stroke is reported. In the treated group mortality in the acute stage in patients with severe strokes was significantly reduced but survivors were severely disabled and six months later no significant benefit could be detected. In less severe strokes no effect of treatment was found. It is concluded that the action of dextran 40 in reducing acute mortality probably lay in preventing or reversing cerebral swelling but no evidence of the expected action in reducing the area of infarction following improved blood flow was found. The importance of extending assessment beyond the two weeks customary in therapeutic trials in stroke is emphasized.

Age Factors↗
PubMed1975

Predicting the outcome of stroke: acute stage after cerebral infarction.

On admission to hospital during the acute phase of a stroke presumed due to ischaemic infarction in one cerebral hemisphere 93 patients were examined to determine the factors associated with a poor prognosis for immediate survival. The patients particularly at risk were those who were overtly unconscious and those with any combination of impaired consciousness, dense hemiplegia, and failure of conjugate ocular gaze towards the side of the limb weakness. Necropsy evidence suggested that these signs usually indicate infarction of the whole of one middle cerebral artery territory which is often secondary to internal carotid artery occlusion and commonly produces fatal cerebral oedema.

Aged↗
PubMed1975

Prognostic factors in stroke.

Prognostic factors in 137 patients with acute ischaemic infarction of the cerebral hemisphere were examined in a prospective study with particular reference to acute mortality, delayed mortality and the ability to regain independent living. Adverse factors in the examination on admission to hospital with regard to all these aspects were found to be a reduction of the level of consciousness to any degree and paralysis of conjugate gaze. A severe hemiplegia and advancing age indicated a bad prognosis for delayed mortality and severe disability in survivors, but did not affect acute mortality. At three weeks after the onset, inability to walk unaided, a useless hand and or urinary incontinence was associated with an increased probability of death in the next few months and of failure to regain independence in the survivors. These adverse factors appeared to correlate with infarction extending beyond the middle cerebral artery territory, severe brain swelling and recent occlusion of the internal carotid artery.

Age Factors↗