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Biomedical subjects

J M Peron

Publications and source records attributed to J M Peron.

At least 37 records · Page 2Linked to original sources
PubMed1994

[Jaffe-Campanacci syndrome. Report of a case].

Jaffe-Campanacci syndrome is a rare entity characterized by disseminated non ossifying fibromas in association with extraskeletal congenital anomalies: cutaneous, genital, ocular and cardiovascular. Mental retardation is also frequently observed. Pathological fractures are the usual mode of revelation. We report one case original because of causal discovery during orthodontic check-up and because of extraskeletal anomalies not previously described. In fact the true incidence of this syndrome is probably underestimated because of unrecognized features.

Abnormalities, Multiple↗
PubMed1993

Acute leukemia after low dose methotrexate therapy in a patient with rheumatoid arthritis.

An 83-year-old woman with seropositive rheumatoid arthritis (RA) developed acute myeloid leukemia after receiving weekly methotrexate (MTX) for 33 months (total dose 690 mg). Although cytogenetic abnormalities typical of damage by cytotoxic agents were not documented, our case may be the first report of acute myeloid leukemia in RA with MTX. We estimate that 6 similar cases should have been observed in France by chance alone. The absence of other reports suggests either that MTX possesses a paradoxical protective effect or that it is not considered a risk factor for malignancy by rheumatologists. Since the number of patients with RA taking MTX can be estimated with reasonable accuracy, the reporting of all suspected cases could help to assess the safety of the drug in rheumatology.

Acute Disease↗
PubMed1989

[Role of the septal cartilage in facial growth. Experimental study in rats].

The authors report a surgical experiment on nasal septal cartilage in the growing rat. Three different operations performed on 95 animals to assess. The role of septal cartilage in facial growth and the effects of standard surgical techniques on facial growth. The results obtained show that sub-periosteal dissection of the nasal bones has no adverse effect on facial growth; conservative procedures such as removal and replacement of septal cartilage, produce minimal effects on facial growth, but large septal cartilage excision obviously impairs facial growth. Guidelines concerning septal surgery in children are suggested in view of these results.

Animals↗
PubMed1987

[Use of the latissimus dorsi myocutaneous flap in cervico-maxillofacial surgery. Study carried out in 32 cases].

The authors report their experience about 32 cases of island latissimus dorsi myocutaneous flaps used in Head and neck reconstruction: 29 where concerning cancer surgery, 3 traumatic after gun shots wounds. The advantages retained for explaining their use of this flap are discussed. The quality of the functional results, the versatility of its use and viability allow them to prefer it to any other one for reconstruction of large head and neck defects.

Adult↗
PubMed1986

[Early radiologic signs of Burkitt's lymphoma].

This paper relates a case of Burkitt lymphoma, whose initial presentation was a deep-bite malformation, that accentuated within a month. Orthodontic consultation referred this 8 years old boy to hospital, where diagnosis was ascertained. The authors discuss radiographs that have been taken before and during the installation of the clinical symptomatology. They point out the main radiographic signs encountered with maxilla involvement in Burkitt lymphoma.

Burkitt Lymphoma↗
PubMed1984

[Lower trapezius musculocutaneous flap for the repair of neoplastic loss of substance of the ear].

Large defects created by oncological resections of the auricular area require to fill and cover the gap to achieve their reconstruction. The lower trapezius myocutaneous island flap meets these two principles more easily and more reliably than previous loco-regional skin flaps. About two patients, who undergone resection of spread carcinoma of the external ear, the authors discuss the advantages and disadvantages of this flap, that appears seldom utilised; they point out some practical problems encountered when raising the flap.

Adult↗
PubMed1984

[Mandibular osteitis and tertiary syphilis].

The authors report the case of a 65 years old man, who suffered from an osteitis, involving the mandible. Within a few months, and despite of a well established treatment, sequestration occurred following a pathologic fracture. No specific germ was encountered after several laboratory examinations. The discovery of a primary syphilis forty years ago, confrontation of clinic and paraclinic data, suggested the actual osteitis could be a complication of tertiary syphilis. A specific treatment was started, and the situation improved progressively. After five months of treatment, mandibular reconstruction was decided. Diagnostic arguments are discussed, and the case is compared with those, not numerous, reported in the literature.

Aged↗
PubMed1984

[Reconstruction of the loss of substance of the lower lip. The "running stairstep" technic].

Reconstruction of near the totality of the lower lip after oncological resection or traumatic amputation, is a very challenging problem. The "step technique", introduced by Johanson, allows a good repair of the amputated lip, regarding amplitude, colour and function. The design of the flaps is recalled; and the authors present two cases which demonstrate the good result obtained with this simple but reliable method.

Aged↗
PubMed1984

[Role of gastroesophageal reflux in acute recurrent laryngeal dyspnea in children].

Recurrent laryngeal croup (RLC) in children is rarely discussed unless permanent laryngeal obstruction is involved or there is an allergic basis. An atypical case is described where gastro-esophageal reflux (GER) was not only associated with but was also directly related to the provocation of each period. A series of 15 patients with RLC were investigated for the presence of GER, and this was confirmed in 7 cases. These findings suggest that GER may be responsible for the onset of RLC, as is now admitted for numerous respiratory manifestations in children. Moreover, GER may be implicated in the course of various laryngeal obstructive lesions, particularly subglottic angioma.

Acute Disease↗
PubMed1982

[Caustic burns of the esophagus in children. Apropos of initial endoscopy and routine sizing].

The advantages and indications for initial endoscopy in esophageal caustic burns in children are discussed in relation to 37 such cases, 13 of which were severe lesions. However, the procedure does not provide initial valid assessment of prognosis in severe 2nd and 3rd degree burns. The definite advantages of early and prolonged esophageal stenting in burns liable to provoke stenosis are emphasized: the esophagus is kept at rest and alimentation by the natural pathways can be maintained. Tubage also avoids gastrostomy or other early surgical procedure in the children, with a subsequent more satisfactory course during dilatations, their frequency thus being diminished. The usual inocuity of sodium hypochlorite after accidental ingestion does not justify endoscopic exploration but esophageal and gastric endoscopic examinations should be performed in all children after ingestion of major caustic agents (soda, acids), whether it is certain or simply suspected that ingestion has occurred, even when clinical signs are absent.

Adolescent↗
PubMed1981

Normal vestibular responses to air caloric tests in children.

One hundred and forty normal children, divided into four age-groups (2-3, 4-5, 6-7, 8-10 years old) have been submitted to a vestibular examination by caloric tests with air, and the responses were recorded. This technique is sure and easily reproducible. Frequency of nystagmus, and maximum eye speed in slow phase of nystagmus (M.E.S.) were examined during 30 sec after caloric stimulation. Frequency of nystagmus increases, and M.E.S. decreases as the children become older. A significant difference between the 2-3 and 4-5 year old groups is also noticed. Normal variations are fixed for each age group. A quantitative relation between frequency, M.E.S. and height is established.

Age Factors↗
PubMed1981

[Mandibular condyle metastasis : report of three cases (author's transl)].

Three cases of mandibular condyle metastasis of particular interest are reported: -- In two out of the three cases they were detected early enough for the primary tumour to be diagnosed; -- they all presented with articular symptoms; -- all three were treated surgically by excision of the condyles. Diagnosis was confirmed by histological examination, a rare event when mandibular metastasis are concerned, these usually being diagnosed after the primary tumour and then irradiated without histological proof. Primary tumours were respectively bronchial, pancreatic, and mammary.

Adenocarcinoma↗