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Biomedical subjects

J M Ramírez-Moreno

Publications and source records attributed to J M Ramírez-Moreno.

14 recordsLinked to original sources
PubMed2005

[Patent foramen ovale and obstructive sleep apnea: their association and meaning].

The patent foramen ovale is a permanent aperture, similar to a floating membrane, remainder from fetal circulation. It can be easily diagnosed by transesophageal echocardiography and/or transcraneal Doppler with contrast. It is being described an increasing number of pathologies, where the presence of a patent foramen ovale can have pathologic significance. The paradoxical embolism considered a rare clinic curiosity, can be an underestimated cause of ischemic stroke. Patients with obstructive sleep apnea present a major prevalence of patent foramen ovale than normal population. In these patients can easily concur, at least theoretically, the basic criteria for paradoxical embolism. In this study, we revised the pathologic implications that can derive from this association.

Foramen Ovale, Patent↗
PubMed2005

[Prevalence of breathing disorders during sleep in patients with cerebrovascular disease].

More of the half of the stroke patients have sleep-disordered breathing. Among them, snoring and the obstructive sleep apnea syndrome (OSAS) have been the most studied. From different epidemiologic studies focused in finding a casual relationship between sleep-disordered breathing and stroke result evidences that at least establish that snoring and principally OSAS are a cause and consequence of stroke. The possibility to modify the respiratory disorder with treatment emphasizes the importance of this association.

Cerebrovascular Disorders↗
PubMedDate not supplied

[Paralysis of the nucleus of the third cranial nerve secondary to a mesencephalic hematoma].

INTRODUCTION: The oculomotor disorders due to mesencephalic pathology are very varied. Function of the third cranial nerve may be affected at the level of the nucleus, in the mesencephalic fascicular portion, interpeduncular fossa, pathway anterior to the posterior communicating artery, sinus cavernosus, sphenoid fissure and orbit. Paralysis of the common oculomotor nerve is the least common of these. Generally it is secondary to ischemic, or sometimes to hemorrhagic vascular pathology. CLINICAL CASE: We present the case of a hypertensive woman with an oculomotor nerve syndrome associated with limitation of horizontal gaze of the contralateral eye and reactive head inclination due to a mesencephalic haematoma. CONCLUSION: The three neuro-ophthalmological findings seen in our patient have rarely been described in the literature. We consider the clinical observation of this case and the study of the organization of the oculomotor nerve nucleus to be of interest for publication.

Aged↗
PubMedDate not supplied

[Chronic inflammatory demyelinating polyneuropathy associated with prostatic adenocarcinoma].

INTRODUCTION AND CLINICAL CASE: Chronic inflammatory demyelinating polyneuropathy (CIDP) is an acquired autoimmune disorder of unknown cause. CIDP most often occurs alone and not as a complication of other disorders but may accompany plasma cell dyscrasias, human immunodeficiency virus infection, systemic lupus erythematosus and others diseases. The association of CIDP and carcinoma has rarely been reported and its relevance is debated. CONCLUSION: We report one patient with CIDP and prostatic adenocarcinoma. Steroids therapy were effective.

Adenocarcinoma↗
PubMedDate not supplied

[SUNCT syndrome and neoplasms in the central nervous system. A new association].

Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) syndrome is a rare form of primary headache disorder, although secondary causes are well known. A growing number of cases have been described since its description in 1978 up to now. We report a new case in a 72 year old woman suffering SUNCT syndrome secondary to two ipsilateral intracranial lesions in the basal portion of the left frontal lobe of the sphenoid wing and the left pontocerebellar angle, suggestive of meningiomas. The patient was successfully treated with carbamazepine. We discuss the differential diagnosis with other very brief headaches associated with cranial autonomic features and the therapeutics possibilities. We review the secondary cases previously reported. The possible pathophysiological mechanism in this case is discussed.

Aged↗
PubMedDate not supplied

[Herpes simplex encephalitis in Cáceres. An analysis of the last five years].

INTRODUCTION: Herpes simplex encephalitis (HSE) is a rare disease, although it is still the most common serious viral infection of the central nervous system. Little is currently known about its epidemiology and clinical features in our area. This paper presents a retrospective description of the clinical, diagnostic and progressive characteristics of patients diagnosed with HSE in Cáceres General Hospital, and confirmed by means of a polymerase chain reaction (PCR) study for the DNA of the herpes simplex virus over the last 5 years. CASE REPORTS: We found four patients who had been diagnosed with HSE in the last 5 years (3.3 cases/million inhabitants/year; CI at 95% of 2.42-4.18), two males and two females, with an age interval between 58 and 75 years. All the patients had high temperatures and three of them also presented neurological focus. A computerised axial tomography scan of the head performed on admission was interpreted as being normal in all cases, while magnetic resonance imaging of the head carried out in two patients showed lesions compatible with HSE in both cases. Electroencephalographic studies were carried out in two patients and revealed focusing in one of them and severe generalised involvement in the other. Analysis of the cerebrospinal fluid (CSF) disclosed lymphocytic meningitis in four cases, although in one of them the study was normal on admission. In two of the patients, viral meningoencephalitis was suspected from the moment the patient was admitted to hospital. For this reason, early treatment with IV acyclovir was established and the clinical progression was good in both patients, although one of them was left with mild neurological sequelae. The other two cases, who died, had a severe underlying pathology and alternative clinical diagnoses that were reasonable on admission (extensive pneumonia and delirium tremens in one of them, and hypercapnic encephalopathy with severe chronic obstructive pulmonary disease in the other), and the clinical suspicion of HSE and the establishment of treatment were late. CONCLUSIONS: The incidence of HSE in our environment is in the upper interval of that reported in the literature. PCR analysis for the herpes simplex virus in CSF seems to have replaced brain biopsy studies as the diagnostic technique. The underlying severe chronic pathology makes it more difficult to diagnose and worsens the prognosis. A multicentre epidemiological study should be conducted to confirm these findings.

Aged↗