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Biomedical subjects

J M Ruiz Liso

Publications and source records attributed to J M Ruiz Liso.

At least 19 recordsLinked to original sources

[Eosinophilic cholecystitis associated with rupture of hepatic hydatid cyst of the bile ducts].

Eosinophilic cholecystitis is a rare finding characterized by an inflammatory infiltrate composed primarily of eosinophils. We report a case of eosinophilic cholecystitis associated with hepatic hydatic cyst ruptured into the biliary tract. The release of hydatid cyst content into the biliary tract may have induced a hypersensitivity reaction with numerous eosinophils in the gallbladder wall.

Bile Ducts, Intrahepatic↗

[Incidence of digestive system neoplasms. Trends. Soria 1981-1990].

The aim of this study was to evaluate, to compare and to identify the various incidence rate trends in digestive tract malignant tumours in the province of Soria. Tumor sites and histological types, patient's age, sex and town and area residence were studied. All new cases of digestive tract malignant tumours were collected during the 1981-1990 period. 30.4% of all malignant tumours in men (1906 patients) and 29% in women (1,256 patients) came from digestive tract sites. Incidence rates for each site were calculated for the two 1981-1985 and 1986-1990 subperiods. The histology, rates and trends of the tumours were compared with the other national and international cancer registries. Gastric cancer showed the highest adjusted rate for men (35.1 x 10(5) and colo-rectal cancer one for women (14.7 x 10(5). The lowest rates were for men in the gallbladder (0.5) and liver (1.1) sites; and for women in the gallbladder (1.6), whose diminishing trend was significant (2.92/0.75) (p < 0.05) and liver (0.5). Colorectal cancer showed a marked increase between the two subperiods for both sexes (men: 13.1/27.6) (women: 9.8/19.2). Pancreas cancer trends ascended for both sexes (men: 1.22/2.74) (women: 0.13/1.46). Gastric cancer rates in Soria are higher than the rest of the cancer registries in Spain while gallbladder, liver, and colorectal, cancer rates are one of the lowest for both sexes. Trends are significantly increasing in colorectal sites for both sexes (p < 0.01), and for women only in the pancreas (p < 0.05). The other cancer rate sites showed lesser variations and are not statistically significant.

Adult↗

[Meningeal carcinomatosis in giant cell lung cancer].

A case of patient with symptoms of L3-L4 roots affliction and IV cranial nerve lesion, caused by meningeal carcinomatosis secondary to giant cell lung cancer, is presented. The clinical features, diagnosis methods, and therapeutic possibilities in this case are commented on.

Carcinoma↗

[Mortality trends caused by neoplasms of the digestive system. Soria, 1950-1985].

The deaths caused by tumours of the digestive system (oesophagus, stomach, colon-rectum, gallbladder and pancreas) recorded in the province of Soria between 1950 and 1985 have been analyzed according to risk and mortality rates. Standardized (adjusted) rates in relation to sex and site of residence (urban-rural) of the deceased were calculated for the decades 1950-1959, 1960-1969, 1970-1979 and the period between 1980 and 1985. Standard errors were calculated to establish confidence limits according to Miettinen's method. The data were obtained from the death certificates of the various registries of the Soria province, including name and surnames, sex, age and site of the tumour according to the 9th revision of the International Classification of Diseases. There is a significant decrease in the mortality risk for tumours of the stomach in both sexes (p less than 0.01) and in liver tumours in females (p less than 0.01). On the other hand, there is an increased risk in both sexes for pancreatic cancer (p less than 0.05 M, p less than 0.01 F) and for oesophageal tumours in men (p less than 0.05). Similarly, during 1980-1985 men were at a significantly greater risk of dying from oesophageal, gastric and liver cancer (p less than 0.01) as well as rectum and colon (p less than 0.05). As far as stomach tumours are concerned there are significant differences between rural and urban areas both in males (p less than 0.01) and in females (p less than 0.05).

Cause of Death↗

[Geographic study of cancer of the stomach in Spain in relation to agricultural activities].

The Spanish provinces with the highest risk of gastric cancer (CG) are in the Castilian meseta, where grain raising predominates. In other countries, high risk areas also correspond to inland, high altitude regions, and in some cases, like Chile, abundant fertilizer consumption. The present study attempts to relate the risk of this tumor in Spain to different types of agricultural activity. Pearson's linear correlation coefficient was calculated between the mortality rate due to gastric cancer in each of the 50 Spanish provinces and the different types of farming and cattle raising activities. The correlation with grain raising on nonirrigated land was positive and significant for mortality in both men (p less than 0.001) and women (p less than 0.01). The correlation between mortality from gastric cancer and cattle raising, particularly sheep, was also positive and significant in both sexes (p less than 0.001). The proportion of the irrigated and nonirrigated fields dedicated to fruit trees correlated negatively with mortality in both sexes, also with a significant difference (p less than 0.01). The authors suggest the need for further epidemiological investigation in Spain, particularly in areas of high risk of gastric cancer, to identify precisely the risk factors that could be related to agricultural activities.

Agriculture↗

[Correlation of the risk of gastric cancer in the province of Soria and the nitrate content of drinking water].

Diverse previous epidemiological studies have associated the risk of gastric cancer (CG) with the nitrate content of drinking water in certain high risk areas in Columbia and Denmark, but in other countries no relation has been found and the topic is still controversial. In the present study and analysis is made of the differential risk of gastric cancer in the province of Soria (Spain) in terms of mortality and incidence in each of the natural regions of this province, investigating an eventual correlation with the nitrate content of the drinking water. Although the maximum nitrate content found barely exceeded the maximum limits suggested by the WHO, these values have a statistically significant positive linear correlation with the adjusted mortality (p less than 0.01) and incidence rates of gastric cancer in men (p less than 0.05). The authors discuss the need for further investigation of the topic in Spain since the nitrate values encountered might not reflect the true magnitude of environmental nitrate exposure, or there could be other factors related to agricultural work in the grain-producing regions where the maximum rates of gastric cancer in men are recorded.

Female↗

[Preneoplastic lesions associated with carcinoma of the stomach: retrospective study of 125 gastrectomy pieces].

A study was made of 125 gastrectomy pieces with gastric carcinoma in which metaplastic and dysplastic changes on the intact gastric mucosa adjacent to the tumor were analyzed. Both incomplete intestinal metaplasia and different types of dysplasia were more frequently and significantly associated with carcinomas of intestinal pattern than with diffuse ones (p less than 0.001). Jass type I dysplasia was more frequent in well-differentiated carcinomas, while Jass type II was more common in relatively undifferentiated tumors, the difference being highly significant (p less than 0.001). Our results and those of other studies in the literature suggest a pathogenic relationship only between preneoplastic lesions and gastric carcinoma of intestinal pattern, which probably includes entities that can be differentiated by pathogenesis to judge from the variations in the dysplastic changes observed.

Aged↗