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Biomedical subjects

J M Shugar

Publications and source records attributed to J M Shugar.

49 records · Page 3Linked to original sources
PubMedDate not supplied

Kissing intrasellar carotid arteries in acromegaly: CT demonstration.

Acromegaly is a disease with protean manifestations that are well described in the literature. One finding infrequently encountered is aneurysmal dilatation of the internal carotid arteries and their branches. A case is presented, with CT documentation, in which the enlarged cavernous portions of the internal carotid arteries prolapsed into the sella turcica and enlarged it. Frontal bossing, frontal sinus enlargement, a dense cortical calvarium, prominent inion, and proptosis secondary to extraocular muscular enlargement were findings also present in this patient. The sella CT appearance has brought the term "kissing intrasellar arteries" to mind to suggest the diagnosis.

Acromegaly↗
PubMedDate not supplied

Benign and malignant parotid pleomorphic adenomas: CT and MR studies.

Parotid pleomorphic adenomas are usually benign, solitary, ovoid masses. Occasionally, these tumors may be highly lobulated and clinically mimic multiple lesions. Actual multiple benign mixed tumors are rare as are malignancies that occur in these pleomorphic adenomas. Of these malignancies, the most common type is the carcinoma ex pleomorphic adenoma. Two patients are presented, one of whom had a markedly lobulated benign mixed tumor and the other patient had an ex pleomorphic malignancy associated with multiple benign mixed tumors. Both cases are documented with CT and magnetic resonance studies. The relative merits of these modalities are discussed as they apply to these parotid masses.

Adenoma, Pleomorphic↗
PubMedDate not supplied

Sternocleidomastoid tumor of infancy: CT manifestations.

A case of sternocleidomastoid tumor of infancy in a 1-month-old boy is presented. Fine-needle aspiration biopsy can be used to confirm the diagnosis and thereby avoid more invasive procedures. Early diagnosis and treatment are important factors in achieving a good clinical outcome.

Head and Neck Neoplasms↗
PubMedDate not supplied

Retropharyngeal mass as a rare presentation of a goiter: CT findings.

When sufficiently large, goiters often extend into the mediastinum. Less often, there is extension into the tracheoesophageal groove and the retroesophageal space, and, rarely, there may be growth into the retropharyngeal space. In the latter instance the goiter will present clinically as an oropharyngeal mass in a patient with stridor. We report two similar cases documented with CT studies that clearly show that the origin of the retropharyngeal mass was the thyroid gland.

Aged↗
PubMedDate not supplied

Single mitotic center for rodent cochlear duct.

The pattern of terminal mitosis in mouse otocyst observed by Ruben led him to postulate the existence of a growth zone at the junction of saccular and cochlear primordia. With the use of colchicine, an antimitotic drug, a localized zone of mitotic activity has been demonstrated at this predicted site.

Animals↗
PubMedDate not supplied

Ewing's sarcoma of the mandible.

Ewing's sarcoma is an uncommon neoplasm that primarily occurs in the long bones of the lower and upper extremities. Only 2% involve the mandible, and the maxilla is involved one eighth as often as the mandible. The most common site of metastases is the lung. Increasing pain is the most common presenting symptom. A case of mandibular involvement is presented. The combination of a large, soft tissue mass adjacent to an area of bone destruction in a young male should suggest the diagnosis. The previously poor five- and ten-year survival rates of 8 and 4% respectively, may have promise of marked improvement. This improvement lies in a changing philosophy of treatment. Four-drug chemotherapy combined with prophylactic whole-lung irradiation has been added to local irradiation of the tumor bed. Five-year survival figures of 20 to 30% appear obtainable. Although extensive surgical resection of the primary tumor in the long bones has for the most part been replaced by local irradiation for control, surgery in mandibular cases may still be the treatment of choice.

Child↗
PubMedDate not supplied

Parotolymphatic backflow: a new sign of malignancy.

The embryology and anatomy of the parotid lymphatics are reviewed. Instances where intraparotid adenopathy can be confused with a parotid tumor are cited. Added to the roentgen signs of parotid malignancy, a new finding, parotolymphatic backflow, is described for what we believe is the first time. Its pathogenesis is discussed.

Humans↗
PubMedDate not supplied

Warthin's tumor, a multifocal disease.

Of all salivary gland neoplasms Warthin's tumor is the only lesion which is truly multicentric. The most common presentation of these multiple lesions is bilateral solitary masses. We present the first reported case of bilateral multiple tumors occurring simultaneously. The embryology of the salivary glands as it relates to the pathogenesis of this tumor is discussed. The differential diagnosis of the multinodular parotid gland is reviewed.

Adenolymphoma↗
PubMedDate not supplied

Metastatic hypernephroma to the head and neck.

Eight cases of metastatic hypernephroma to the head and neck are presented with CT documentation. Hypernephroma is the third most common infraclavicular tumor to metastasize to the head and neck. Such metastases occur in about 15% of patients with this neoplasm, and nearly 8% of patients with this tumor present with disease in the head and neck region. These metastases are usually vascular and may either clinically precede the diagnosis of the renal primary tumor or may occur many years after apparently successful surgery of the primary tumor. These unusual patterns of behavior are reviewed. One of the cases presented here is the first reported incidence of cervical lymph node metastasis with hemorrhage to be documented by CT, thus adding this entity to the list of imaging differential diagnoses of cystic-appearing neck masses.

Angiography↗