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J M Struthers

Publications and source records attributed to J M Struthers.

2 recordsLinked to original sources

Visual evoked potentials and visual processing in stimulant drug-exposed infants.

Prenatal exposure to cocaine and amphetamines has been associated with many adverse effects in infants, including neurological abnormalities. Recent evidence shows that the visual system may be useful in infancy to evaluate neurological functioning. Visual evoked potentials (VEPs) and visual recognition memory testing were carried out on eight infants with prenatal drug-exposure and eight controls, matched for ethnicity and socio-economic status. The drug-exposed infants performed significantly worse on the visual recognition test. However, there were no differences between groups on VEP testing and no correlations between tests. The results suggest that the difficulties found in visual recognition memory of drug-exposed infants are not related to neurological maturity, as measured by VEPs.

Amphetamines↗

Visual recognition memory in drug-exposed infants.

Visual recognition memory testing in high-risk infants has been shown to have significant predictive ability for later cognitive deficits. This study evaluated cognition in infants exposed prenatally to illicit stimulant drugs compared with nonexposed controls with a standardized test of visual recognition, the Fagan Test of Infant Intelligence (FTII). Thirty-six healthy, full-term infants with prenatal exposure to cocaine and/or amphetamines and 26 infants with no drug exposures, matched for race and socioeconomic status, were tested. Average FTII scores were significantly lower and the percentage testing at risk significantly higher in the drug-exposed group (p less than .01). Differences between groups were also noted in behaviors dealing with attention, distractibility, and activity level. These data support recent evidence from longitudinal studies showing that infants exposed to drugs prenatally may be at risk for later subtle neurological abnormalities and suggest these difficulties may be identifiable long before the children reach school age.

Amphetamine↗