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Biomedical subjects

J M Toomey

Publications and source records attributed to J M Toomey.

41 records · Page 3Linked to original sources

Clinical course of unusual malignant sarcomas of head and neck.

The clinical manifestations of 29 recently encountered sarcomas of the head and neck were analyzed in an attempt to define more accurately the diagnostic characteristics and therapeutic responses of these unusual tumors. The host factors of age, sex distribution, race, habits and associated features differ sufficiently to distinguish the sarcoma from the carcinoma population. In addition, the clinical course of sarcoma patients as monitored by mode of presentation, site of involvement, tumor histology, diagnostic features and certain elements of management and outcome, further indicates that these tumors can be defined and managed as a distinct group of lesions. A review of the recent literature supports the major conclusions of this study.

Adolescent↗

Malignant fibrous histiocytoma of the larynx.

Fibrous histiocytoma is a rare mesenchymal tumor. The origin is believed to be a pleuri-potential cell, histiocytic in type, which can evolve into a facultative fibroblast under certain conditions. A case of a malignant fibrous histiocytoma in the subglottic larynx is reported. At present, the clinical behavior and degree of malignancy cannot be predicted. It appears that wide, local excision of the tumor with a margin of normal tissue is the treatment of choice. Regional block dissection of lymph nodes is not indicated unless clinically palpable nodes are present.

Adult↗

Vasodilating agents in augmentation of skin flap survival.

Skin flap necrosis is a serious problem in reconstructive head and neck surgery. Currently, the only clinically effective means of preventing flap necrosis is delay. Hypothesized mechanisms of delayed and experimental methods of increasing flap survival are discussed. Investigative data supporting the use of phentolamine to augment flap survival are presented.

Animals↗

Concurrent toxoplasmosis and feline infectious peritonitis in a cat.

A 13-year-old, 4-kg, neutered male Maine coon presented with ascites. Toxoplasma gondii tachyzoites were seen within neutrophils and macrophages, and free within the abdominal fluid. At necropsy, many abdominal organs were positive for feline infectious peritonitis (FIP) antigens using immunohistochemical staining. This apparently is the first report of concurrent toxoplasmosis and FIP in a domestic cat.

Animals↗