Transposing the urethral meatus in the treatment of recurrent and postcoital cystitis in women with hypospadias.
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Biomedical subjects
Publications and source records attributed to J M Weir.
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To evaluate in a prospective study the sensitivity of urine and spermatic fluid cultures in identifying the presence of infection compared to Meares-Stamey's test (MSt) results. Fourty patients were diagnosed having bacterial prostatitis following MSt. They underwent both urine and spermatic fluid cultures after MSt results and immediately before antibiotic treatment. All the patients were asked which of the three examens was the least tolerable. Urine and spermatic fluid culture were negative in 36 and 4 cases respectively. Spermatic fluid culture identified infection in 36 out of 40 patients who underwent MSt (90%) and was more acceptable for the patients. Urine culture is a less accurate way of identifying the infective agent in prostatitis, compared to spermatic fluid culture. The latter procedure is similar to the MSt.
Testicular microlithiasis is a rare pathology which usually affects both testicles (less than 100 cases have been described in the literature), histologically characterized by numerous calcified deposits situated inside the seminiferous tubules, the diameter of which does not usually exceed 2 mm. The pathogenesis of the phenomenon is not completely clear; it has however been noted that there is a higher incidence in patients affected by cryptorchidism, subfertility, Klinefelter's syndrome and in particular those with testicular neoplasms, although the reason for this remains obscure. The case reported seems atypical in that there is no association with the conditions mentioned above and the finding is monolateral, something which is unusual in the literature reviewed.
Eighteen patients with inflammatory process of the prostate met criteria for the inclusion in the study: 1) non bacterial prostatitis; 2) no previous treatment. Then they were randomized into three groups as it follows: terazosine, tamsulosin and placebo. Alpha-blockers and placebo were given for two months, after which further uroflowmetry was performed. Symptom score was evaluated before and after treatment. Terazosine was effective in reducing TO (p = 0.01) as tamsulosin and placebo did not. Both terazosine (p = 0.034) and tamsulosin (p = 0.006) reduced max TQ as placebo did not. Symptom score significantly improved in patients receiving terazosine (p = 0.0002) and tamsulosin (p = 0.001) while insignificantly in whose receiving placebo.
The Authors report two cases of renal leiomyosarcomas with atypical clinical features. Despite a malignant histological picture, nephron-sparing surgery was performed. The two patients are alive and disease-free at six years and fifteen months respectively. Specific radiologic findings, indications and rationale for conservative treatment are discussed.
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