Vesiculopapular eruption in an infant. Histiocytosis X.
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Female↗
Biomedical subjects
J M Weitzner
Publications and source records attributed to J M Weitzner.
Ichthyosis follicularis in two girls: an autosomal dominant disorder.
Ichthyosis follicularis (IF) is a rare disorder of keratinization that has been described primarily in males and proposed as a possible X-linked disorder. We report two black girls with nonscarring alopecia; photophobia; follicular hyperkeratoses; hyperkeratosis of the extensor aspects of the hands, knees, and elbows; fixed, erythematous, perineal plaques; and angular cheilitis who seem to fit the clinical criteria for IF. One girl also had gingival hypertrophy and a hearing deficit. One child's father had identical symptoms. We propose that these girls may have a variant of IF that is inherited as an autosomal dominant trait.
Alopecia↗
Alopecia areata.
Alopecia areata is an asymptomatic, nonscarring hair loss with spontaneous remissions and exacerbations. Although the etiology is unknown, the disorder is associated with vitiligo, atopy, pernicious anemia, Down syndrome and thyroiditis. The area of hair loss may remain localized or may involve the entire scalp or all body hair. Treatment is difficult to assess because of individual response and spontaneous remissions, as well as a high rate of relapse. Intralesional injection of corticosteroids is the most common mode of treatment, although systemic steroid therapy, contact allergens, minoxidil, psoralens plus ultraviolet light, and other agents have been tried.
Adjuvants, Immunologic↗
Successful treatment of botryomycosis in a patient with acquired immunodeficiency syndrome.
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Acquired Immunodeficiency Syndrome↗
Pediatric bowenoid papulosis: risks and management.
A 34-month-old Haitian girl had a six-month history of asymptomatic vulvar papules. Histologic features and DNA probe studies were diagnostic of bowenoid papulosis. Resolution of the lesions was enhanced by cryotherapy. This is the third reported patient with prepubertal bowenoid papulosis. Sexual abuse should be suspected, but not assumed, in pediatric patients with this condition. Our patient had no evidence of sexual abuse. Bowenoid papulosis has been associated with cervical intraepithelial neoplasia and rarely with squamous cell carcinoma. Close gynecologic follow-up is recommended.
Bowen's Disease↗
Vesicular scabies in an adult.
We describe an unusual vesicular eruption occurring secondary to scabies in an elderly patient receiving high-dose prednisone therapy.
Aged↗