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J Macfall

Publications and source records attributed to J Macfall.

2 recordsLinked to original sources

Fast spin-echo high-resolution MR imaging of the inner ear.

Advances in MR imaging continue to improve our ability to evaluate temporal bone anatomy and disease. CT remains the procedure of choice for fine-detail imaging of bone structures such as ossicular anatomy, but it is not the ideal imaging technique for soft-tissue structures (e.g., the membranous labyrinth and neural structures). Conventional spin-echo MR techniques used to image these structures cannot yield excellent contrast and spatial resolution in clinically acceptable time frames. Conventional spin-echo T1-weighted images lack tissue contrast between fluid (e.g., CSF, endolymph, perilymph), neural tissue, otic capsule septa, and surrounding temporal bone. Conventional T2-weighted imaging of the inner ear is needed to reveal the natural contrast between fluid, neural structures, and bone; unfortunately, the use of conventional T2-weighted images is limited by time constraints when large-matrix, thin-section techniques with more than one excitation are used. Fast spin-echo imaging is a recently developed technique that can provide T2-weighted, thin-section (2-mm) high-resolution images with excellent contrast in a fraction of the time needed for conventional spin-echo techniques. This speed advantage allows us to obtain high-resolution images in clinically acceptable time frames. Images produced by this technique are a useful addition, in conjunction with routine T1- and T2-weighted spin-echo images, in the diagnosis of disorders of the inner ear.

Adult↗

Verification of a hyperthermia model method using MR thermometry.

Simulation of hyperthermia induced power and temperature distributions is becoming generally accepted and finding its way into clinical hyperthermia treatments. Such simulations provide a means for understanding the complete three-dimensional temperature distribution. However, the results of the simulation studies should be regarded with caution since modelling errors will result in differences between the actual and simulated temperature distribution. This study uses a diffusion weighted magnetic resonance (MR) based technique to measure hyperthermia induced temperature distributions in a three-dimensional space in a non-perfused phantom. The measured data are used to verify the accuracy of numerical simulations of the same three-dimensional temperature distributions. The simulation algorithm is a finite element based method that first computes the electromagnetic induced power deposition then the temperature distribution. Two non-perfused phantom studies were performed and qualitatively the MR and simulated distributions agreed for steady-state. However, due to the long MR sampling time (approximately 4 min), poor agreement between the simulations and MR measurements were obtained for thermal transients. Good agreement between the simulations and fibreoptic thermometry measurements were obtained. The fiberoptic measurements differed from the simulations by 0.11 +/- 0.59 degrees C and -0.17 +/- 0.29 degrees C (mean +/- standard deviation for the two studies).

Algorithms↗