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Biomedical subjects

J Madelain

Publications and source records attributed to J Madelain.

At least 19 recordsLinked to original sources

[Results of systematic preventive treatment with argon laser after idiopathic retinal detachment].

Incidence of spontaneous second retinal detachment ranged from 10 to 19%. We reported a retrospective study of 527 rhegmatogenous retinal detachments. At the end of this study 302 second eyes with an average follow up of 46 months have been analysed. 205 second eyes were treated systematically by 360 degrees equatorial Argon Laser Photocoagulation (ALP) completed by four anterior radial rows independently of evidence or lack of peripheral retinal degenerations or retinal breaks. The incidence of bilateral retinal detachment decreased from 11 to 2.4% when systematical prophylactic treatment has been applied. After prophylactic treatment, no complications could be certainly attribute to ALP. This study contributed to ascertain safety and effectiveness of systematical prophylactic treatment by ALP.

Adult↗

[Spontaneous rupture of Bruch's membrane and transient macular hemorrhage in patients with myopia].

18 eyes of 14 pathologic myopia patients with lacker cracks have been studied during a mean follow up of 45 months by initial and final clinical and fluoroangiography evaluation. These lacker cracks happen early in the myopia degeneration evolution in young patients. The evolution is marked by transient coinlike macular hemorrhages without CNM detectable. Prognosis for the retention of central vision after macular hemorrhages resolution is good. It mainly depends of lacker cracks initial location if macular quite wrong, if intramacular, quite right. Development of CNM is an infrequent eventuality but must be systematically research by angio-fluorography after spontaneous macular hemorrhage resolution which usually occurs 4 or 6 weeks later.

Adolescent↗

[Asteroid hyalitis: an uncommon complication of retinal telangiectasis].

The authors report a case of asteroid hyalosis which required a vitrectomy because of the decreased vision. The vitrectomy places in a prominent position an epi-macular membrane which has been peeling during the procedure and retinal vascular malformations like "telangiectasies" which are the starting point of other complications.

Adult↗

[Primary palpebral localization of a trabecular Merkel cell carcinoma (1 case)].

We report one case of Merkel cell carcinoma. They commonly arise on the eyelids of elderly patients. Others localisations are on the skin of the pelvis. Clinical aspects, histological study, associating morphological aspect, ultra-structural and immuno-histo-chemical studies are characteristics enough to differentiate this tumor others tumors of the skin like cutaneous malignant lymphoma. The origin of this tumor is still discussed, but sure neuro-endocrinal. Possibility of visceral metastases on a small number of cases (6 to 8%) must be consider when treated. Total surgical ablation should be obtained.

Adenocarcinoma↗

[Malignant transformation of a nevus of ota].

The association of naevus of Ota and choroidal melanoma is reported in a 83 years-old monophtalm caucasian man. Because of no tumoral spreading in this monophtalm patient, the tumor is treated by physical technique with iridium disc. In the next months, complications of this physical treatment appeared. The authors remind the clinical aspect of the disease and the different associations, also that the frequency of coming of the main complication of the affection: the choroidal melanoma.

Aged↗

[Adenoma of the retinal pigment epithelium].

We report 3 cases of macular or perimacular adenomas of the R.P.E. These tumors are small, deeply pigmented and arise abruptly like a pyramid from a flat base over laying retina. There is no intra-tumoral vascularisation during angiography. They typically grow very slowly or not. Metastasis from them has never been described like a certainty with histological evidence. Clinical course, histological aspects are very similar to a carcinoma of R.P.E. They have a tubular or cord-like arrangement of proliferated R.P.E. cells. The main problem is to differentiate these tumors from first malignant melanomas and other uveal pigmented tumors and second others nonneoplastic proliferations of R.P.E.: essentially unifocal congenital hypertrophy and reactive hyperplasia. Management of these tumors depends of clinical characteristics and often behavior of the tumor with periodical photographic or ultrasonic supervision to detect evidence of growth which could lead to enucleation to obtain histologic evidence for fear of uveal malignant tumor.

Adenocarcinoma↗