PubMed Health⌕ Search

Biomedical subjects

J Magri

Publications and source records attributed to J Magri.

6 recordsLinked to original sources
PubMed2003

Lead and other metals in gestational hypertension.

OBJECTIVES: To identify any effects that lead, calcium, magnesium, and zinc may have on the development of gestational hypertension. METHODS: Third-trimester 110 normotensive and 33 gestational hypertension cases were assayed for various metal levels, using standard techniques, including atomic absorption spectrometry. RESULTS: Gestational hypertension cases showed significantly higher blood lead levels than normotensives. No differences were noticed regarding calcium (ionized and total), magnesium, and zinc levels. Blood lead was significantly related with blood pressure, even after correcting for the body mass indices and age. Blood pressure levels showed no relation to the other analyzed metals. However, the lead:ionized calcium ratio showed a stronger association with blood pressure, than lead alone. Blood lead showed a significant negative relationship with ionized calcium, but none with the other metals. CONCLUSIONS: Blood lead evidently influenced blood pressure increments and gestational hypertension development. This implies that all efforts should be made to reduce the population's exposure.

Adult↗
PubMed1975

Suprapubic prostatectomy combined with vesico-urethroplasty.

A new look at the operation of suprapublic prostatectomy is suggested in view of the continuing substantial morbidity associated with traditional techniques. The proposition is that a reconstructive as distinct from a simple ablative operation is possible, notwithstanding long-standing beliefs to the contrary. The writer goes on to outline the principles, and to describe and illustrate in detail the steps in a new technique of prostatectomy combined with a urethroplasty, which uses full-thickness bladder wall flaps to provide immediate epithelial cover for the denuded surfaces of the prostatic urethra. The theoretical advantages of such a technique are borne out by the results in the first 400 cases so treated, which are contrasted with those from a comparable personal series of 200 retropubic prostatectomies and other representative series.

Age Factors↗
PubMed1975

Hydrogen ion transport in the rabbit esophagus.

The lumen of the rabbit esophagus was perfused in vivo with solutions (one solution per esophagus) containing 0-160 mM HCl by a constant circulation technique for 5 h. During the 1st h, net H+ flux out of the lumen (efflux) was minimal at H+ concentrations of 80 mM or less, but increased linearly with increase in luminal H+ concentrations above 80 mM. After 3 h, the net H+ efflux increased proprtionately to increasing H+ concentrations above a threshold of 20 mM. At the 5th h a linear relationship between net H+ efflux and luminal concentration was seen at all concentrations. Histological damage accompanied increase in H+ efflux and correlated with luminal acid concentrations and duration of exposure. We conclude that the rabbit esophageal mucosa is essentially impermeable to H+ below a threshold concentration of 80 mM for up to 1 h of exposure. When exposure is prolonged, this threshold steadily decreases with time. The occurrence of passive H+ diffusion above threshold concentrations most probably results from an increase in mucosal permeability, possibly an initiating event in the genesis of esophagitis.

Animals↗